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    Mogila A.A.

    GONARTHRITIS:EXUDATE OR TRANSUDATE?


    About the author: Mogila A.A.
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation The study of joints has significantly improved over the past few decades from arthroplasty and biopsy to the use of arthroscopic and ultrasoundographic technologies that facilitate visualization and increase the reliability of synovial biopsy. But it is necessary to note a certain lack of understanding of some significant points about the causes and the development of synovitis. Our study provides a new understanding of the origin of this pathology and a new look at the solution to the problem of treating this disease. Objective: To explain the analysis of synovial fluid and determine the cause of its formation by the example of synovitis of the knee joint. The presence of lactate in the synovial fluid, we regarded as a direct sign that the synovial fluid is lactate. There are also indirect indications that the synovial fluid is lactic acid. We decided to find out if there is synovitis of the knee joint with an inflammatory effusion, as previously thought, or, according to our hypothesis, synovitis is lactic acid, which comes from the muscles.
    Tags synovitis, synovial fluid, knee joint, ultrasound diagnosis, exudate, transudate, lactic acid
    Bibliography
    • Gumerov P. A. Sovremennyie metodyi diagnostiki i lecheniya sinovita kolennogo sustava / R. A. Gumerov, A. A. Abzalilov // Kazanskiy med. zhurnal. – 2006. – T. 87, prilozhenie. – S. 30–31.
    • Dotsenko T. G. Issledovanie sinovialnoy zhidkosti – klinicheskaya znachimost poluchennyih rezultatov / T. G. Dotsenko, G. I. Shlyikova, O. V. Teplyakova // Klinicheskaya laboratornaya diagnostika. – 2016. – No. 8. – C. 478–484.
    • Lukashenko L. V. Surfaktantnoe sostoyanie sinovialnoy zhidkosti u bolnyih revmatoidnyim gonitom / L. V. Lukashenko // Bol. Sustavyi. Pozvonochnik. – 2013. – No. 1 (09). – S. 25–29.
    • Matveeva E. L. Biohimicheskie izmeneniya v sinovialnoy zhidkosti pri razvitii degenerativno-distroficheskih protsessov v kolennom sustave: avtoref. dis. na soiskanie stepeni doktora biolog. nauk: spets. 03.00.04 «Biohimiya» / E. L. Matveeva // – Kurgan, - 2007. – 24 s.
    • Mogila A. A. Opredelenie zavisimosti vyirazhennosti sinoviita kolennogo sustava ot stepeni myishechno-tonicheskogo sindroma polupereponchatoy i medialnoy ikronozhnoy myishtsi metodom ultrazvukovogo skanirovaniya / A. A. Mogila // Svit meditsini ta biologiyi. – 2017. – No. 2 (60). – S. 92–97.
    • Mogila A. A. Opredelenie stepeni sinoviita kolennogo sustava v zavisimosti ot vesa patsienta metodom UZD / A. A. Mogila // Svit meditsini ta biologiyi. – 2017. – No. 2 (60). – S. 88–92.
    • Mogila A. A. Strukturnyie izmeneniya myishechno-suhozhilnogo kompleksa, opredelyaemyie ultrazvukovyim skanirovaniem pri nespetsificheskom sinoviite kolennogo sustava / A. A. Mogila // Visnik problem biologiyi i meditsini. – 2017. – Vip. 1 (135). – S. 152–157.
    • Mohyla O. O. Miazovo-tonichnyi syndrom miaziv-zghynachiv stehna ta homilky yak prychyna utvorennia ta rostu kisty Beikera. Za rezultatamy ultrazvukovoho skanuvannia / O. O. Mohyla // Visnyk problem biolohii ta medytsyny. – 2017. – Vyp. 3, t.1 (137). – S. 180–186.
    • Olyunin Yu. A. Hronicheskiy sinovit v revmatologii. Otsenka aktivnosti i taktika lecheniya // Russkiy meditsinskiy zhurnal. – 2005. – Tom 13, No. 8. – S 548-551.
    • Pavlova V. N. Sinovialnaya sreda sustava / V. N. Pavlova // – Moskva: Meditsina, - 1980. – 296 s.
    • Perfilova L. V. Novyie aspektyi diagnostiki sinovita kolennogo sustava u bolnyih revmatoidnyim artritom / L. V. Perfilova // Visnik ortopediyi, travmatologiyi ta protezuvannya. – 2012. – No. 2 (73). – S. 57–59.
    • Chernyakova Yu. M. Sinovialnaya zhidkost: sostav, svoystva, laboratornyie metodyi issledovaniya / Yu. M. Chernyakova, E. A. Sementovskaya // Meditsinskie novosti. – 2005. – No. 2. – S. 9–14.
    • Albro M. B. Shearing of Synovial Fluid Activates Latent TGF-β / M. B. Albro, A. D. Cigan, R. J. Nims [et al.] // Osteoarthritis Cartilage. – 2012. – Vol. 20 (11). – P. 1374–1382.
    • Awisat A. Pseudoseptic Arthritis with Low Synovial Fluid Glucose in Familial Mediterranean Fever / A. Awisat, G. Slobodin, N. Jiries [et al.] // Isr Med Assoc J. – 2017. – Vol. 19 (7). – P .461–462.
    • Ding J. Expression of synovial fluid biomarkers in patients with knee osteoarthritis and meniscus injury / J. Ding, X. Niu, Y. Su [et al.] // Exp Ther Med. – 2017. – Vol. 14 (2). – P. 1609–1613. doi: 10.3892/etm.2017.4636.
    • Orr C. Synovial tissue research: a state-of-the-art review / C. Orr, E. Sousa, D. L. Boyle [et al.] // Nat Rev Rheumatol. – 2017. – Vol. 13 (8). – P. 463–475. doi: 10.1038/nrrheum.
    • Tan W. M. Proteomic Analysis of Synovial Fluid Obtained From a Dog Diagnosed With Idiopathic Immune-Mediated Polyarthritis / W. M. Tan, S. F. Lau, M. Ajat [et al.] // Top Companion Anim Med. – 2017. – Vol. 32 (1). – P. 24–27. doi: 10.1053/j.tcam.2017.05.002
    • Wu C.-L. Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair / C.-L. Wu, K. A. Kimmerling, D. Little [et al.] // Sci Rep. – 2017. – N 7. – 44315 p.
    Publication of the article «World of Medicine and Biology» №3(61), 2017 year, 041-044 pages, index UDK 616.728.3-002-073.48
    DOI 10.26724/2079-8334-2017-3-61-41-44