EnglishУкраїнська
  • Main
  • Useful links
  • Information for Contributors
  • About
  • Editorial board

  • Article
    N. Yu. Emelyanova, V. Yu. Galchinskaya, T. N. Bondar

    FEATURES OF THE METABOLISM OF NITRIC OXIDE IN PERIODONTAL DISEASES IN PATIENTS WITH COPD IN COMBINATION WITH CHD


    About the author: N. Yu. Emelyanova, V. Yu. Galchinskaya, T. N. Bondar
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation The paper considered the role of nitric oxide in the pathology of periodontal tissues in patients with chronic obstructive pulmonary disease (COPD) in combination with coronary heart disease (CHD). It was found that in the blood plasma there was a decrease of total level of stable metabolites in patients with COPD as compared to the control group, as well as a significant increase of expression of inducible NO synthase in the materials the gingival mucosa.
    Tags chronic obstructive pulmonary disease, periodontitis, stable metabolites of nitric oxide, NO-synthase
    Bibliography
    • Beloklitskaya GF, Asharenkova OV, Protunkevich OO, Pavlenko EM. Osobennosti metabolizma oksida azota pri ispolzovanii na etape etiotropnogo lecheniya bolnyih generalizovannyim parodontitom (faza I) gigienicheskogo kompleksa „Colgate®”. Sovrem. stomatol. 2012; 2: 35- 38.
    • Gurevich MA, Dolgova EV, Kuzmenko NA. Hronicheskie obstruktivnyie zabolevaniya legkih, arterialnaya gipertenziya i ishemicheskaya bolezn serdtsa: osobennosti patogeneza, klinicheskoy kartinyi, terapii. RMZh. 2016; 16: 1098-1102.
    • Efimov VV, Blazhko VI, Voeykova LS, Krahmalova EO, Talalay IV, Bondar TN. Pokazateli funktsii endoteliya u bolnyih HOZL razlichnoy stepeni tyazhesti. Ukrayinskiy pulmonologichniy zhurnal. 2005; 4: 44-47.
    • Zubachyk VM, Yarychkivska NV. Rol oksydu azotu v homeostazi tkanyn parodonta. Bukovynskyi medychnyi visnyk. 2016; T.20; 2 (78): 194-198.
    • Kiselyk IO, Lutsyk MD, Shevchenko LIu. Osoblyvosti vyznachennia nitrativ ta nitrytiv u krovi khvorykh na virusni hepatyty ta zhovtianytsi inshoi etiolohii. Laboratorna diahnostyka.2001; 3: 43-45.
    • Kubyisheva NI, Postnikova LB, Soodaeva SK, Novikov VV. Znachenie rastvorimyih molekul kletochnoy adgezii, metabolitov oksida azota, endoteliina-1 i ih assotsiatsiy kak markerov progressirovaniya vospaleniya pri HOBL. Sovremennyie tehnologii v meditsine. 2017; 9(2): 105–117.
    • Lopushkova YuE, Shilina E. Osobennosti endotelialnoy funktsii u bolnyih hronicheskoy serdechnoy nedostatochnostyu i hronicheskoy obstruktivnoy boleznyu legkih. Vestnik VolgGMU. 2017; 2 (62): 74- 77.
    • Nazaryan RS, Krivenko LS, Gargin VV. Tkanevaya aktivnost sintazyi oksida azota v rotovoy polosti pri atopicheskoy patologii Morfologiya. 2016; Tom: 10; 3: 212-216 .
    • Shenkman BS, Lomonosova YuN, Nemirovskaya TL. Neyronalnaya NOsintaza – molekulyarnyiy garant stabilnosti myishechnogo volokna: NOzavisimyie signalnyie puti v aktivnoy i razgruzhennoy myishtse. Uspehi fiziologicheskih nauk. 2014; 45 (2): 37–48.
    • Corradi M, Pesci A, Casana R. Nitrate in exhaled breath condensate of patients with different airway diseases. Nitric Oxide. 2003; 8 (1): 26–30.
    • Carratu P., Scoditti C, Maniscalco M. Exhaled and arterial levels of endotelinare increased and correlate with pulmonary systolic pressure in COPD with pulmonary hypertension. BMC Pulm. Med. 2008; 8 (5): 154– 158.
    • Folkerts G, Kloek J, Muijsers RB, Nijkamp FP. Reactive nitrogen and oxygen species in airway inflammation. Eur. J.Pharmacol. 2001; 429: 251– 262.
    • GOLD -Global Initiative for Chronic Obstructive Lung Diseases (updated 2011-2015)
    • Kanazawa H, Shiraishi S, Hirata K, Yoshikawa J. Imbalance between levels of nitrogen oxides and peroxynitrite inhibitory activity in chronic obstructive pulmonary disease. Thorax. 2003; 58: 106–109.
    • Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology.Pharmacol Rev.1991;43:109-142.
    • Menaka KB, Ramesh A, Thomas B, Kumari NS. Estimation of NO as an inflammatory marker in periodontitis. J. Indian. Soc. Periodontal. 2009; 13: 75-78.
    • Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med. 2001; 163(5):1256-1276.9.
    • Yeramian A, Martin L, Serrat N. Arginine transport via cationic amino acid transporter 2 plays a critical regulatory role in classical or alternative activation of macrophages. J. Immunol. 2006; 176: 5918-5924.
    Publication of the article «World of Medicine and Biology» №1(63), 2018 year, 028-031 pages, index UDK 616.314.18-002.4-092:616.24-007.272-036.11:616-005.4
    DOI 10.26724/2079-8334-2018-1-63-28-31