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    І.І.Starchenko, А.B. Korobchanska 1, N.I. Vynnyk, M.M. Koptev, S.M. Sovgirya


    About the author: І.І.Starchenko, А.B. Korobchanska 1, N.I. Vynnyk, M.M. Koptev, S.M. Sovgirya
    Type of article Scentific article
    Annotation The paper presents the analysis of the current studies of the urinary bladder pathologies that occur in the clinical practice. The novel theories of the UB damage and the disorders of the urodynamics are impressive by its complexity and diversity. Understanding the causes and ways of the development of UB pathological processes is crucial in the correct and timely diagnosis and further therapeutic management, resulting in the improving of patient’s quality of life. In particular, the analysis and study of some of the discoveries made by the scholars that form an understanding of the development of inflammatory, nonplastic and dysfunctional pathology of the bladder is presented. The paper highlighted the differential diagnosis of the inflammatory pseudotumor, pathogenesis of the overactive bladder, clinical and morphological picture of rare malignant tumors. The role of the advanced morphological studies in the diagnosis of the UB disease is emphasized.
    Tags urinary bladder, urological pathology, overactive bladder, obstruction, inflammation, tumors, environmental pollution
    • Rosado E, Pereira J, Corbusier F, Demeter P, Bali MA. Inflammatory Pseudotumor of the Urinary Bladder. J Radiol Case Rep. 2015; 9(1): 36–42. doi: 10.3941/jrcr.v9i1.2066.
    • Forner S, Andrade EL, Martini AC, Bento AF, Medeiros R, Koepp J et al. Effects of kinin B1 and B2 receptor antagonists on overactive urinary bladder syndrome induced by spinal cord injury in rats. Br J Pharmacol. 2012; 167(8): 1737–52. doi: 10.1111/j.1476-5381.2012.02127.x.
    • Girard BM, Tooke K, Vizzard MA. PACAP/ Receptor System in Urinary Bladder Dysfunction and Pelvic Pain Following Urinary Bladder Inflammation or Stress. Front Syst Neurosci. 2017; 11: 90. doi: 10.3389/fnsys.2017.00090.
    • Corcos J, Przydacz M, Campeau L, Witten J, Hickling D, Honeine С et al. CUA guideline on adult overactive bladder. Can Urol Assoc J. 2017; 11(5): E142–E173. doi:  10.5489/cuaj.4586.
    • De Groat WC, Griffiths D, Yoshimura N. Neural Control of the Lower Urinary Tract.Compr Physiol. 2015; 5(1): 327–96. doi:  10.1002/cphy.c130056
    • Boopathi E, Gomes C, Zderic SA, Malkowicz В, Chakrabarti R, Patel DP et al. Mechanical stretch upregulates proteins involved in Ca2+ sensitization in urinary bladder smooth muscle hypertrophy. Am J Physiol Cell Physiol. 2014 Sep 15; 307(6): C542–C553.
    • Lin W, Rahman NA, Lin J, Zhang Н, Gou К, Yu W et al. Molecular Mechanisms of Bladder Outlet Obstruction in Transgenic Male Mice Overexpressing Aromatase (Cyp19a1). Am J Pathol. 2011 Mar; 178(3): 1233–44. doi:  10.1016/j.ajpath.2010.11.056.
    • Haddad-Lacle JE, Haddad CJ, Villas B. A rare urinary bladder tumour. BMJ Case Rep. 2014; 2014: bcr2013202994. doi:  10.1136/bcr-2013-202994.
    • Liang X, Wang Y,Zhang J, Cheng Н, Wang J, Dang Y et al. Anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma with involvement of the urinary bladder: a case report and review of literature. Onco Targets Ther. 2015; 8: 1143–47.
    • Kinney MC, Higgins RA, Medina EA. Anaplastic large cell lymphoma: twenty-five years of discovery. Arch Pathol Lab Med. 2011; 135 (1): 19–43.
    • Kozyrakis D, Petraki C, Prombonas I, Grigorakis A, Kanellis G. Lymphoepithelioma-like bladder cancer: clinicopathologic study of six cases. Int J Urol. 2011; 18: 731–34. doi: 10.1111/j.1442-2042.2011.02825.x.
    • Rosado E,Pereira J, Corbusier F, Demeter P, Bali M. Lymphoepithelioma-like carcinoma of the urinary bladder: a case report and review of the literature. BMC Res Notes. 2014; 7: 779. doi:  10.1186/1756-0500-7-779.
    • Venyo A.K. Melanoma of the Urinary Bladder: A Review of the Literature. Surg Res Pract. 2014; 2014: 605802. doi:  10.1155/2014/605802.
    • Meunier R, Pareek G, Amin A. Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the Literature.Case Rep Pathol. 2015: 173870. doi: 10.1155/2015/173870.
    • Truong H, Sundi D, Sopko N, Xing D, Lipson EJ, Bivalacqua TJ. A Case Report of Primary Recurrent Malignant Melanoma of the Urinary Bladder. Urol Case Rep. 2013 Dec; 1 (1): 2–4.
    • Theocharides C, Chatzopoulos K, Papanikolaou D, Siokas V, Amplianitis I, Papanikolaou A. Metastatic Melanoma to the Urinary Bladder of Ocular Origin Accompanied with Primary Cutaneous Melanoma: Diagnostic Challenge—A Report of a Case. Case Rep Pathol. 2017; 2017: 4818537. doi:  10.1155/2017/4818537.
    • Romaniuk А, Lyndin M, Smiyanov V, Sikora V, Rieznik A, Kuzenko Y et al. Primary multiple tumor with affection of the thyroid gland, uterus, urinary bladder, mammary gland and other organs. Pathol Res Pract. 2017 May; 213(5): 574-79. doi: 10.1016/j.prp.2017.01.003.
    • Romaniuk A, Lyndin M, Sikora V, Piddubnyi A, Budko H, Volkogon A. Multifocal primary tumour with lesions in prostate gland and urinary bladder: clinical case. Bangladesh Journal of Medical Science.2017; 16 (1): 161-5.
    • Viveka BK, Amirtham U, Kumar VM, Babu GK.A case of synchronous double malignancy: Invasive bladder cancer and Leiomyosarcoma of extremity and review of literature South Asian J Cancer. 2013 Jul-Sep; 2(3): 152.
    • Al-Zalabani A, Stewart KFJ, Wesselius A, Schols AMWJ, Zeegers MP. Modifiable risk factors for the prevention of bladder cancer: a systematic review of meta-analyses. Eur J Epidemiol. 2016; 31(9): 811–51.
    • Hung R, Boffetta P, Brennan P, Malaveille C, Hautefeuille A, Donato F et al. GST, NAT, SULT1A1, CYP1B1 genetic polymorphisms, interactions with environmental exposures and bladder cancer risk in a high-risk population. IntJCancer.2004;110: 598–604.
    • Rorbach-Dolata A, Marchewka Z, Piwowar A. The biochemical carcinogenesis of selected heavy metals in bladder cancer. Postepy Biochem. 2015; 61 (2): 176-82.
    • Letašiová S, Medveďová A, Šovčíková A, Dušinská М,Volkovová К, Mosoiuet C et al. Bladder cancer, a review of the environmental risk factors. Environ Health. 2012; 11 (Suppl 1): S11. doi:  10.1186/1476-069X-11-S1-S11.
    • Lubet RA, Scheiman JM, Bode A, White J, Minasian L, Juliana ММ et al. Prevention of Chemically-Induced Urinary Bladder Cancers by Naproxen: Protocols to Reduce Gastric Toxicity in Humans Do Not Alter Preventive Efficacy. Cancer Prev Res. 2015; 8(4): 296–302.
    • Kobayashi T, Owczarek TB, McKiernan JM, Abate-Shen C. Modeling bladder cancer in mice: opportunities and challenges. Nat Rev Cancer. 2015; 15(1): 42–54.
    • Capasso A, Raiano V, Sontuoso A, Olivero D, Greci V. Fibrosarcoma of the urinary bladder in a cat. JFMS Open Rep. 2015 Jan-Jun; 1(1): 2055116915585019. doi: 10.1177/2055116915585019.
    • Maiolino P, Özkul A, Sepici-Dincel A, Roperto F, Yücel G, Russo V et al. Bovine Papillomavirus Type 2 Infection and Microscopic Patterns of Urothelial Tumors of the Urinary Bladder in Water Buffaloes. Biomed Res Int. 2013; 2013: 937918. doi:  10.1155/2013/937918.
    Publication of the article «World of Medicine and Biology» №1(63), 2018 year, 192-196 pages, index UDK 616.62 – 07
    DOI 10.267254/2079-8334-2018-1-63-192-196