I.V. Rudenko, V.K. Lihachov, V.P. Mischenko, M.Y. Golubenko, Y.Y. Shymanska

MEDICO-GENETIC DIAGNOSIS OF HEREDITARY PREDISPOSITION TO NONCARRYING OF PREGNANCY AND REPRODUCTIVE LOSSES

---

About the author:	I.V. Rudenko, V.K. Lihachov, V.P. Mischenko, M.Y. Golubenko, Y.Y. Shymanska
Heading	CLINICAL MEDICINE
Type of article	Scentific article
Annotation	The analysis of genetic models (gene grids) of genes associated with the risk for noncarrying of pregnancy: 2 collagen (COL2A1 6846C/A), plasminogen activator inhibitor-1 (RAI-1 PLANH1), superoxide dismutase (SOD1 7958 G/A), glutathione S-transferase (GSTμ1), N-acetyltransferase 2 (NAT2) has been carried out in 327 women. Their role in reproductive losses has been shown.
Tags	medicogenetic diagnosis, hereditary predisposition, noncarrying of pregnancy, reproductive losses
Bibliography	Baranov VS., Ivashchenko TE., GlotovAS. Opredeleniye nasledstvennoy predraspolozhennosti k nekotorym chastym zabolevaniyam pri beremennosti. Geneticheskaya karta reproduktivnogo zdorov'ya. SPb: Izd-vo N-L; 2009. 68 s. [in Russian] Likhachev VK. Prakticheskoye akusherstvo s neotlozhnymi sostoyaniyami. Moskva: Meditsinskoye informatsionnoye agentstvo; 2010. 20-22. [in Russian] Likhachev VK. Prakticheskaya ginekologiya s neotlozhnymi sostoyaniyami. Moskva: Meditsinskoye informatsionnoye agentstvo; 2013. 753-4. [in Russian] Yemets NA. Preyemstvennost' sokhranyayushchey terapii u zhenshchin s ugrozoy preryvaniya beremennosti. Z turbotoyu pro zhínku. 2016 Sentyabr' 18;6(72):13-15. [in Russian] Semenyuk LN., Lihachev VK. Recovery ovulation in women with obesity, PCOS and pregnancy lose a history. Australian Journal of Scientific Research. 2014 January-june 5; 1(5):132-8. Zimmern RL. The clinical use of genetics and molecular biomarkers: a public health perspectives. Europ. J. Human Genetics. 2008 Jan 12; 16: 7-12.
Publication of the article	«World of Medicine and Biology» №2(64), 2018 year, 075-077 pages, index UDK 618.3/5:612.6.05]-07
DOI	10.26724/2079-8334-2018-2-64-75-77