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    O. M. Didushko, P. R. Herych, I. V. Cherniavska, R.I. Yatsyshyn, V.I. Pankiv

    INFLUENCE OF THE COMPLEX TREATMENT OF HYPOTHYROIDISM ON THE LEPTIN LEVEL IN PATIENTS WITH PRIMARY HYPOTHYROIDISM


    About the author: O. M. Didushko, P. R. Herych, I. V. Cherniavska, R.I. Yatsyshyn, V.I. Pankiv
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation The total of 188 patients with primary hypothyroidism and 30 people without an impaired function of thyroid gland were examined and compared according to sex and age. While evaluating leptin level in blood serum of patients with hypothyroidism, we noticed that an increase of the body mass in these patients is accompanied by the growth of its concentration. We revealed a more expressed hyperleptinemia in patients with postsurgical hypothyroidism. Basic treatment with levothyroxine and especially its comorbidity with atorvastatin contributed to the improvement of the clinical state of the patients, to the decrease of hypothyroidism manifestations, to the decrease of body mass. Addition of atorvastatin to the complex treatment had a significant impact on the leptin level in patients with hypothyroidism and obesity independently from hypothyroidism etiology.
    Tags Hypothyroidism, hyperleptinemia, obesity, treatment
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    Publication of the article «World of Medicine and Biology» №3(65), 2018 year, 059-063 pages, index UDK 616-08+616.441-008.64+616-056.52
    DOI 10.26724/2079-8334-2018-3-65-59-63