Dubyna V.A., Skrypnykov P.N., Khavalkina, L.M., Korobeinikova Yu.L.

SUBSTANTIATION OF USE OF NANOPREPARATION IN COMPLEX TREATMENT OF PATIENTS WITH CHRONIC GENERALIZED PERIODONTITIS OF I-II DEGREE

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About the author:	Dubyna V.A., Skrypnykov P.N., Khavalkina, L.M., Korobeinikova Yu.L.
Heading	CLINICAL MEDICINE
Type of article	Scentific article
Annotation	Currently, periodontal disease is rating first among dental diseases. Among all known treatment methods, in complex therapy the leading one is local therapeutic treatment with various preparations, the choice of which should be based on the degree and form of the pathology and severity of the course of chronic generalized periodontitis (CGP). In our study we used nanopreparation called Fullerene-C60. Good tolerability and safety of the preparation in treatment of CGP allows us to consider it as a non-injectable alternative to conventional methods of treatment. The nanopreparation was used in the irrigator and in the form of instillations / applications (or their combination) in each periodontal pocket. The area of protein fractals before and after administration of Fullerene-C60 has been studied. The findings of the study showed that the protein fractal area in two groups decreased on the average by 2.480%. The use of Fullerene-C60 in the form of irrigation and instillation / applications showed a clear decrease in the area of protein fractals in tiziographic samples, which proves the rational use of this nanopreparation.
Tags	Fullerene-C60 nanopreparation, periodontitis, biofilm
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Publication of the article	«World of Medicine and Biology» №3(69), 2019 year, 063-066 pages, index UDK 616.314.17-085
DOI	10.26724/2079-8334-2019-3-69-63-66