| About the author: |
Schnаider S.A., Suslova O.V., Savelieva N.N., Anisimov M.V., Maslov A.V., Noneva N.O., Tkachenko E.K. |
| Heading |
EXPERIMENTAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The total of 25 white rats males 1.5-2 - months of age were included in the experiment. Intact group comprised 7 specimens. In the control group, a model of periodontitis was reproduced (7) with administering pelentan per os and replacement of drinking water with 2% EDTA ad libitum. The hormonal forms of vitamin D3 were administered per os in doses per rat a day: 0.1 μg 1.25(OH)2D3 (5 animals) and 1.25 μg 24.25(OH)2D3 (6 animals) together with Vicasolum at a dose of 1.5 mg for 60 days. The hormonal forms of vitamin D3 with Vicasolum showed anti-osteo-resorptive, periodontal protective properties, which resulted in a decrease in the level of periodontal bone resorption, LPO products; activation of antioxidant enzymes; increasing the level of sulfhydryl groups of proteins in the mucous membrane of the oral cavity and the alveolar bone. |
| Tags |
hormonal forms of cholecalciferol, vitamin K, lipid peroxidation, periodontal protective properties, antioxidant enzymes, sulfhydryl groups of proteins, rats |
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| Publication of the article |
«World of Medicine and Biology» №3(69), 2019 year, 234-238 pages, index UDK (615.356.577.16)-092.19:616.314.17-008.1:599.238 |
| DOI |
10.26724/2079-8334-2019-3-69-234-238 |
