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    Kurylo Kh.I., Nebesna Z.M., Klishch I.M., Volska A.S.

    CORRECTIVE EFFECT OF PHOTOCOMPOSITION ON THE NON-ENZYMATIC GLYCOSYLATION PROCESSES AND STRUCTURAL CHANGES IN THE PANCREAS IN EXPERIMENTAL TYPE 2 DIABETES MELLITUS


    About the author: Kurylo Kh.I., Nebesna Z.M., Klishch I.M., Volska A.S.
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation In experimental conditions, on the model of type 2 diabetes mellitus in rats, the effect of goat’s rue (Galega officinalis) based phytocomposition on the processes of non-enzymatic glycosylation, as well as on the morphological state of the pancreatic endocrine apparatus was carried out. It was established that the goat’s rue based phytocomposition and its liposomal form Halevit has a pronounced stabilizing effect on the carbohydrate metabolism disorders and morphological condition of the pancreas endocrine apparatus in the conditions of experimental type 2 diabetes mellitus. At the same time, on the basis of micromorphometric analysis, it can be concluded that the expression of the positive effect on the condition of the rat pancreas’ endocrine part in experimental type 2 diabetes mellitus, the new Halevit composition is dominated by a phytochemical based on goat’s rue.
    Tags pancreas, streptotrozine, type 2 diabetes mellitus, goat’s rue, blueberry, taurine, liposomal form
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    Publication of the article «World of Medicine and Biology» №4(70), 2019 year, 198-203 pages, index UDK 616.37-091.8-02:616.379-008.64-084
    DOI 10.26724/2079-8334-2019-4-70-198-203