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    Nezgoda I.I., Havryliuk A.O., Asaulenko A.A., Kholod L.P., Onofriichuk O.S., Naumenko O.M.

    MEASLES PNEUMONIA IN CHILDREN: CLINICAL AND MORPHOLOGICAL FEATURES OF THE COURSE


    About the author: Nezgoda I.I., Havryliuk A.O., Asaulenko A.A., Kholod L.P., Onofriichuk O.S., Naumenko O.M.
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation The article presents the results of a retrospective analysis of 96 patients’ histories with measles established, with a detailed course study and the anamnestic data analysis. The measles infection course was accompanied with signs of the intoxication syndrome, the classic catarrhal triad manifestation (coughing, rhinorrhea and conjunctivitis), and the exanthema syndrome. Most of the diseased children are not vaccinated against measles. The patients had a complicated disease course with manifested symptoms of measles pneumonia, as the most common complication in this pathology. Morphological and histological changes of the lungs in children with severe mesles course were characterized by abundant infiltration of both the interalveolar septa and alveolar lumens by polymorphocellular infiltrate, consisting of neutrophilic leukocytes, eosinophils, lympho-histiocytes with numerous parietal hyaline masses (hyaline membranes). There was a giant-cell metaplasia of the alveolar epithelium.
    Tags measles in children, pneumonia, pathomorphological changes, histological examination
    Bibliography
    • Hnatyuk VV, Pokrovska TV. Uskladnennya koru v ditey i doroslykh Buk. Med. Visnyk. 2015; 19, 2 (74): 48-51. [in Ukrainian]
    • Yevropeyskoye regionalnoye byuro VOZ. Epidemiologicheskaya spravka VOZ. 2018;2:1-11. Dostupno na: www.euro.who.int/data/assets/pdffile/0005/386708/epibrief2rus.pdf [in Russian]
    • Maydannyk VH, Yemchynska YeO. Klinichni nastanovy z diahnostyky ta likuvannya pozalikarnyanoyi pnevmoniyi u ditey z pozytsiyi dokazovoyi medytsyny. Kyiv, 2014. 43 s. [in Ukrainian]
    • Marusyk UI. Kir u ditey. Aktualnaya Infektologiya. 2017; 5:129-33. doi: 10.22141/2312-413x.5.3.2017.109855 [in Ukrainian]
    • Alexander KC Leung, KL Hon, KF Leong, CM Sergi. Measles: a disease often forgotten but not gone. Hong Kong Med J. 2018;24:512–20 Available from: https://www.ncbi.nlm.nih.gov/pubmed/30245481 DOI: 10.12809/hkmj187470
    • Department of Health. Melbourne, Victoria, Australia. Infectious Diseases Epidemiology & Surveillance. Measles (rubeola) [Internet]. Available from: http://www.health.vic.gov.au/ideas/ bluebook /measles
    • Laksono MB, de Vries RD, McQuaid S, Duprex WP, de Swart RL. Measles Virus Host Invasion and Pathogenesis / Received: 2 June 2016; Accepted: 21 July 2016; Published: 28 July 2016 doi:10.3390/v8080210
    • Lindberg C, Lanzi M, Lindberg K. Measles: Still a significant health threat. American journal of maternal child nursing. June 2015 DOI: 10.1097/NMC.0000000000000162. https://www.researchgate.net/publication/279303385
    • Medić S, Petrović V, Lončarević G, Kanazir M, Begović Lazarević I, Rakić Adrović S, et al. Epidemiological, clinical and laboratory characteristics of the measles resurgence in the Republic of Serbia in 2014-2015. 2019; PLoS ONE 14 (10): e0224009. Available at: https://doi.org/10.1371/journal. pone.0224009
    • Rafat C, MD, Klouche K, MD, Ricard J, MD, PhD, Messika J, MD, Roch A, MD,PhD, Machado S, MD,et al. Severe Measles Infection. The Spectrum of Disease in 36 Critically Ill Adult Patients. Medicine/ Volume 92, Number 5, September 2013; р.257-272; DOI: 10.1097/MD.0b013e3182a713c2
    • Selina SP Chen, MD. Measles Clinical Presentation. MPH. Updated: Jun 06, 2019. https://emedicine.medscape.com/ article/966220-clinical
    • Végh M, Hári-Kovács A, Roth H-W, Facskó A, Orv H. Ophthalmological symptoms of measles and their treatment. 2017; 158(39): 1523–1527. DOI: 10.1556/650.2017.30852
    Publication of the article «World of Medicine and Biology» №1(71), 2020 year, 088-093 pages, index UDK 616.915/.24-002-053
    DOI 10.26724/2079-8334-2020-1-71-88-93