EnglishУкраїнська
  • Main
  • Useful links
  • Information for Contributors
  • About
  • Editorial board

  • Article
    Popovych І.Yu., Petrushanko Т.О., Yeroshenko G.А.

    PECULIARITIES OF PORCINE PERIODONTIUM IN NORMAL CONDITION AND IN GENERALIZED PERIODONTITIS DURING DENTAL RESTORATION OF VARIOUS TYPES


    About the author: Popovych І.Yu., Petrushanko Т.О., Yeroshenko G.А.
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation The paper was aimed at determining the structural features of porcine gums in normal conditions and experimental generalized periodontitis in the presence of adhesive bridges and dental implants. It is established, that impaired differentiation in the form of dyskeratosis occurs in the epithelium of the gingival mucosa of pigs with generalized periodontitis; it is manifested by the appearance of basal cells in the cytograms that are absent in the control group of animals, and 4-fold increase in the number of parabasal epitheliocytes. Histological study of the mucous membrane of the epithelial plate revealed vacuolar dystrophy of the cells in the spinous layer and local phenomena of spongiosis. In their lamina propria, disorders of microcirculation and connective tissue edema were noted. Changes in the lamina propria during dental restoration of different types were common. In the epithelium, during restoration with dental implant, the changes corresponded to the control group: vacuole dystrophy and local spongiosis. Marked hyperkeratosis in the epithelial plate was noted in restoration with bridge denture.
    Tags experimental generalized periodontitis, adhesive bridge-like structures, dental implants, cytograms, gums, pigs
    Bibliography
    • Vasilyeva LV. Klinicheskie i funktsionalno-morfologicheskie izmeneniya v parodonte u voennosluzhashchih Sukhoputnykh Voysk pri kompleksnom lechenii parodontita i parodontoza. [dissertatsіya]. Sank-Peterburg; 2009. 144 s. [in Russian]
    • Gasyuk NV, Yeroshenko GA, Palіy OV. Suchasnі uyavlennya pro etіolohіyu ta patohenez khvorob parodonta. Svіt medicini ta bіolohiyi. 2013; 2 (38): 203–207. [in Ukrainian]
    • Lapach SN, Chubenko AV, Babich PN. Statisticheskie metody v mediko-biologicheskikh issledovaniyakh s ispolzovaniem Exel. Kiev: Morion; 2000. 320 s. [in Russian]
    • Obshchie eticheskie printsipy eksperimentov na zhivotnykh: materialy I Natsionalnogo kongressa po bioetike. Kyiv: NANU. 2001. 16 s. [in Ukrainian]
    • Shylivskyy IV, Nemesh OM, Honta ZM. Suchasni pohlyady na etiolohiyu ta patohenez zapalnykh zakhvoryuvan parodonta, yikh vzayemozvyazok iz patolohiyeyu sechovydilnoyi systemy (ohlyad literatury ta vlasni doslidzhennya). Bukovynskyy medychnyy visnyk. 2016; 20(1):224-7. [in Ukrainian]
    • Ban A, Nemeth ZF, Szauter A, Soos S, Balasko M. Prevalence and severity of chronic paradontitis and oral mucosal lesions in chronic obstructive lung disease. Orvosi hetilap. 2018; 159(21):831-6.
    • Cheremisina VF; Bereznyakova AI. Correlation of cytokine products levels in regulation mechanisms of bone tissue remodeling processes in parodontitis. World of medicine and biology. 2018; 64 (2):181-5.
    • Demkovych AE, Bondarenko YuI, Hasiuk, PA. Humoral immune reactivity disorders in experimental periodontitis and their correction by flavonol. World of medicine and biology. 2017; 61 (3): 97-100.
    • Detert J, Pischon N, Burmester GR, Buttgereit F. Pathogenesis of periodontitis in rheumatic diseases. Zeitschrift fur rheumatologie. 2010; 69 (2): 109-14.
    • Gasyuk NV, Yeroshenko GA. Feature of cellular composition of the gums in generalized periodontitis. World of medicine and biology. 2015, 1 (48): 17–20.
    • Kutepov IV, Lyashev YD, Artyushkova EB, Solin AV, Serikov VS, Lyashev AY, et al. Correction of acute parodontitis with indolicidin analogues. Bulletin of experimental biology and medicine. 2019; 167(1):47-9.
    • Müller F, Shimazaki Y, Kahabuka F, Schimmel M. Oral health for an ageing population: the importance of a natural dentition in older adults. Int Dent J. 2017;67(2):7-13.
    Publication of the article «World of Medicine and Biology» №1(71), 2020 year, 206-210 pages, index UDK 616.311.2/.314.17:636.4
    DOI 10.26724/2079-8334-2020-1-71-206-210