| About the author: |
Yareshko A.G., Kulish M.V. |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The immunostimulating effect of corticosteroids in the complex treatment of tuberculosis patients when they are administered in a double physiological dose, every other day, taking into account the circadian rhythm of the function of the hypothalamic-pituitary-adrenal axis was substantiated in the article. Whereas with daily administration, corticosteroids have shown an immunosuppressive effect. Peripheral blood B-lymphocytes are not sensitive to glucocorticosteroid drugs. |
| Tags |
tuberculosis, pathogenetic therapy, glucocorticosteroids |
| Bibliography |
- Barkanova ON, Gagarina SG, Kaluzhenina AA. Steroidnyi tuberkulez. Medical sciences/Colloquium-journal. 2020; 5(57):30-2. [in Russian]
- German A.O. Pokazateli tsitokinovoy aktivnosti pri vpervye diagnostirovannom tuberkuleze legkikh s razlichnoy chuvstvitelnostyu k khimiopreparatam v zavisimosti ot pokazateley tireoidnogo gomeostaza i soderzhaniya kortizola. Zhurnal Grodnenskogo gosudarstvennogo meditsinskogo universiteta. 2015; 1:79-82. [in Russian]
- Kuzhko MM, Prosvyetov YuV, Gulchuk NM, Avramchuk OV, Gusarova AYu. Efektivnist likuvannya ta profilaktika alergichnykh uskladnen u khvorykh na tuberkuloz lehen. Astma ta alerhiya. 2014; 1:30-4. [in Ukrainian]
- Kuznetsova LV, Frolova VM, Babadzhan VD, redaktori. Klinichna ta laboratorna imunolohiya. Natsionalnyi pidruchnyk. Kyiv: OOO “Poligraf plus”; 2012. 922 s. [in Ukrainian]
- Kulish MV. Glyukokortikoyidy yak zasib patohenetychnoyi terapiyi tuberkulozu. Svit medytsyny ta biolohiyi. 2013; 40(3):88-91. [in Ukrainian]
- Litvinenko AV. Obshchie printsipy sistemnoy glyukokortikosteroidnoy terapii. Ukrayinskiy pulmonologichnyi zhurnal. 2014; 1:60-4. [in Russian]
- Maksimov GV, Mukomolov SL, Ivanov AK. Bezopasnost terapii prednizolonom v lechenii bolnykh tuberkulezom i VICh-infektsiey. Infektsiya i immunitet. 2013; 3(4):341–6. [in Russian]
- Mordyk AV, Batisheva TL, Bryuhanova NS, Puzyreva L.V. Vliyanie immunologicheskih narusheniy na khod vpervye vyyavlennogo infiltrativnogo tuberkuleza u sotsialno sohranennykh patsientov. Infektsiya i immunitet. 2014; 4(4):353-8. [in Russian]
- Poletaeva AV, Levanyuk AI, Sergeeva EV. Vliyanie gormonov na immunologicheskuyu reaktivnost. Obzor. Ekologiya cheloveka. 2009; 7:42-6. [in Russian]
- Protsyuk RG, Zaguta YuB. Funkcionalniy stan adrenokortikalnoyi sistemy u hvorykh z ko-infektsiyeyu tuberkulozu VIL. Tuberkuloz, lehenevi khvoroby, VIL-infekciya. 2015; 4(23):12-5. [in Ukrainian]
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| Publication of the article |
«World of Medicine and Biology» №3(73), 2020 year, 144-148 pages, index UDK 616.24-002.5:615.37 |
| DOI |
10.26724/2079-8334-2020-3-73-144-148 |
