About the author: |
O.I. Ryabukha |
Heading |
EXPERIMENTAL MEDICINE |
Type of article |
Scentific article |
Annotation |
Hypothyroidism occupies the major place among all disorders of the thyroid gland. The reason for this is both extensive iodine deficiency areas and the influence of natural and artificial goitrogens. The purpose of the study was to compare the effect of organic and inorganic iodine on the hormonal activity of the thyroid glands in white nonlinear male rats, which were under the conditions of alimentary iodine deficiency, potentiated by mercazolilum. Because the intensity of thyroidal colloid amino acids iodination is equivalent to the activity of hormone production, the thyroid gland activity was determined histochemically by the method of A. DesMarais & Q.N. LaHam. It was determined that organic iodine activates the thyroid gland’s hormonal activity more than inorganic iodine, while taking organic iodine the histochemical picture of the thyroid gland depended on the dose of iodine consumed and tended to normalize with its increase. |
Tags |
thyroid gland, follicular thyrocyte, thyroidal colloid, organic iodine, inorganic iodine, iodine deficiency |
Bibliography |
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Publication of the article |
«World of Medicine and Biology» №4(74), 2020 year, 193-198 pages, index UDK 616.441-008.64-018:(547.226+546.15) |
DOI |
10.26724/2079-8334-2020-4-74-193-198 |