| About the author: |
O. G. Boychuk-Tovsta, O. G. Boychuk, T. Ya. Divnych, O. M. Ilnytska, A. B. Kostyshyn, O. M. Vynogradova |
| Heading |
EXPERIMENTAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
Pregnancy due to its physiological course is supported by intensification of all kinds of intechanges including both macroelement and trace element ones. Metal imbalance is closely connected to the activity of some enzymes, vitamins and metallobiotics (iron, magnesium, cuprum and zink). The violation of the microelements’ interchange, which have a huge bioactivity is connected with the impact on metabolism, sanguification, tissue respiration, determines its vital role in pathogenesis of many illnesses including periodontitis. As a result, providing mineral homeostasis is more special and complicated during pregnancy, especially one that is affected by iron deficiency. The research of serum mineral interchange proved that imbalance of trace elements (microelementosis) is essential component of iron deficiency, pathogenesis in pregnant women and it strengthens according to the development of generalized periodontitis. Iron and cuprum biometals deficiency, especially important during pregnancy, turned to be particularly keen. We have observed the gradual decrease of the content of biometals in serum in both groups of the survey with the development of generalized periodontitis. So, iron deficiency anemia leads to disorders of mineral homeostasis of oral fluid and blood serum, and the progression of generalized periodontitis increases the deficiency of trace elements in the these biological fluids. |
| Tags |
pregnant women, iron deficiency, generalized periodontitis, trace elements, blood, oral fluid |
| Bibliography |
- Borysenko AV, Mahomedova OM, Timokhina TA. Pokaznyky metabolizmu spoluchnoyi tkanyny ta mineralnoho obminu v patsiyentok z heneralizovanym parodontytom na tli ZDA. Sovremennaya stomatologiya. 2011 (3): 63–6. [In Ukrainian]
- Yesaulenko EE, Yerychev YV. Byokhymyia rotovoi y desnevoi zhydkosty: uchebnoe posobye. 2008. Krasnodar; 100 s. [In Russian]
- AlJehani Y. Risk Factors of Periodontal Disease: Review of the Literature. Int J Dent. 2014; 2014: 182513 Published online 2014 May 20. doi: 10.1155/2014/182513
- Blumsohn A. Serum osteoprotegerin as a determinant of bone metabolism in a longitudinal study of human pregnancy and lactation. Journal of Clinical Endocrinology Metababolism. 2013. 88: 5361–65.
- Daalderop LA, Wieland BV, Tomsin К, Reyes L. Periodontal Disease and Pregnancy Outcomes: Overview of Systematic Reviews. JDR Clin Trans Res. 2018 Jan; 3(1): 10–27. Published online 2017 Sep 25. doi: 10.1177/2380084417731097PMCID: PMC6191679.
- Dukić L, Kopčinović L, Dorotić A, Baršić I. Blood gas testing and related measurements: National recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Biochem Med (Zagreb) 2016 Oct 15; 26(3): 318–336. Published online 2016 Oct 15. doi: 10.11613/BM.2016.036 PMCID: PMC5082214
- Dwivedi AK, Shukla R. Evidence‐based statistical analysis and methods in biomedical research (SAMBR) checklists according to design features. Cancer Rep (Hoboken) 2020 Aug; 3(4): e1211. Published online 2019 Aug 22. doi: 10.1002/cnr2.1211 PMCID: PMC7941456.
- Johnson M, George А, Dahlen Н, Ajwani S. The midwifery initiated oral health-dental service protocol: an intervention to improve oral health outcomes for pregnant women. BMC OralHealth. 2015; 15: 2. Published online 2015 15. DOI: 10.1186/1472-6831-15-2 PMCID: PMC4324677
- Kalkwarf HJ, Specker BL. Bone mineral changes during pregnancy and lactation. Endocrine. 2013.17: 49–53.
- Krleza J, Dorotic A, Grzunov A, Maradin M. Capillary blood sampling: national recommendations on behalf of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Biochem Med(Zagreb) 2015 Oct 15; 25(3): 335–358. Published online 2015 Oct 15. doi: 10.11613/BM.2015.034 PMCID: PMC4622200
- Laur N, Kinscherf R, Pomytkin K, Kaiser L, Knes O, Deigner H. ICP-MS trace element analysis in serum and whole blood. PLoS One. 2020; 15(5): e0233357. Published online 2020 May 20. doi: 10.1371/journal.pone.0233357 PMCID: PMC7239469.
- Makeeva IM, Ignatko AA, Churganova AA, Lebedev VA, Makeeva MK. Periodontal diseases and complicated pregnancy. Stomatologiya(Mosk). 2019;98(1):70-73. doi: 10.17116/stomat20199801170.
- Nazir MA, Izhar F,Akhtar K, Almas K. Dentists' awareness about the link between oral and systemic health. J Family Community Med. 2019 Sep–Dec;26(3):206–212. doi: 10.4103/jfcm.JFCM_55_19.
- Vesper H, Myers GL, Miller WG. Current practices and challenges in the standardization and harmonization of clinical laboratory tests. Am J Clin Nutr. 2016 Sep; 104(Suppl 3): 907S–912S. Published online 2016 Aug 17. doi: 10.3945/ajcn.115.110387 PMCID: PMC5004491
- Zipporah I, Middleton Р, Esposito М. Treating periodontal disease for preventing adverse birth outcomes in pregnant women. Cochrane Oral Health Group Cochrane Database SystRev. 2017 Jun; 2017(6): CD005297. Published online 2017 Jun 12. doi: 10.1002/14651858.CD005297.pub3 PMCID: PMC6481493
|
| Publication of the article |
«World of Medicine and Biology» №2(76), 2021 year, 178-182 pages, index UDK 616.311.2-002+616.314.17-008.6)]-06:616.155.194.8-02:618.3-06]-07:(616.152+616.316-008.8)]-07 |
| DOI |
10.26724/2079-8334-2021-2-76-178-182 |
