English Українська
  • Main
  • Useful links
  • Information for Contributors
  • About
  • Editorial board

  • Article
    M. Sh. Hilmutdinova, L. D. Chebotar, V. S. Cherno

    STATE OF OXIDATIVE METABOLISM IN HEART AND SKELETAL MUSCLE TISSUES OF RATS UNDER CONTINUOUS LIGHTING


    About the author: M. Sh. Hilmutdinova, L. D. Chebotar, V. S. Cherno
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation The article considers and compares the features of oxidative metabolism of cardiac and skeletal muscle tissue under the changed photoperiod conditions, influenced by continuous lighting. It is shown that under the conditions of continuous lighting in the studied tissues there is an imbalance in the “prooxidants-antioxidants” system, a shift of balance towards peroxidation processes, which is manifested in increased generation of reactive oxygen species, increased concentration of peroxide oxidation secondary products, decreased activity of some antioxidant enzymes in the cardiac muscle tissue. In its turn, in the skeletal muscle tissue, a shift in balance is manifested in the decreased activity of some antioxidant enzymes.
    Tags prooxidant-antioxidant balance, lipid peroxidation, cardiac muscle tissue, skeletal muscle tissue, photoperiod
    Bibliography
    • Arushanyan EB, Beyer EV. Gormon mozgovoy zhelezy epifiza melatonyn – unyversalnyi yestestvennyi adaptogen. Uspekhi fiziologicheskikh nauk. 2012;  43, 3: 82–100. [In Russian]
    • Arushanyan EB, Shchetynyn EV. Melatonyn kak unyversalnyi modulyator lyubykh patologicheskikh protsessov. Patologicheskaya fiziologiya i eksperimentalnaya terapiya. 2016; 60, 1: 9–88. [In Russian]
    • Bondarenko LO, Mishchenko TV, Poltorak VV, Sotnyk NM. Khronobiologichni aspekty vplyvu melatoninu na okremi skladovi metabolichnoho syndromu pry hipopinealizmi. Problemy endokrynnoyi patolohiyi. 2015; 3:  85–93. [In Ukrainian]
    • Gromova DS, Belyakova VY. Vliyaniye razlichnoy prodolzhitelnosti fotoperioda na povedencheskiye reaktsii krys i osobennosti ikh korrektsii preparatom melaksen. Vestnik meditsinskogo instytutaREAVIZ. 2012; 1: 33–37. [In Russian]
    • Gubina-Vakulyk GY, Milovidova AE, Kolousova NG. Vliyaniye soderzhaniya eksperymentalnykh zhyvotnykh v usloviyakh dlitelnogo postoyannogo osveshcheniya na slizistuyu obolochku zheludka. Svetovoy rezhim, starenie i rak : sbornik nauchnykh trudov II Rossiyskogo simpoziuma s mezhdunarodnym uchastiem (Petrozavodsk, 17-19 oktyabrya 2013 goda). Petrozavodsk, 2013: 55-61. [In Russian]
    • Lotosh TA, Vinogradova YA, Anisimov VN y dr. Postoyannoye osveshchenye kak faktor prezhdevremennogo stareniya. Rol nachala vozdeystviya. Svetovoy rezhim, stareniye i rak : sbornik nauchnykh trudov II Rossiyskogo simpoziuma s mezhdunarodnym uchastiem (Petrozavodsk, 17-19 okt. 2013 g.).Petrozavodsk, 2013: 204–212. [In Russian]
    • Nepomnyashchikh SF, Gutsol LO, Kuklina LB, Gaskova NP. Stress kak mekhanizm adaptatsii, yego narusheniya i ikh farmakologicheskaya korrektsiya. Almanakh sestrinskogo dela. 2014; 2:  4–8. [In Russian]
    • Pishak VP, Bulyk RYe. Shyshkopodibna zaloza – golovnyi endokrynnyi organizator bilyadobovoho periodyzmu. Integratyvna antropologiya. 2011; 2: 32–37. [In Ukrainian]
    • Sokolenko VL. Vplyv faktoriv stresovoyi pryrody na pokaznyky imunnoyi systemy. Visnyk Cherkaskoho universytetu. 2015; 19: 110–114. [In Ukrainian]
    • Chabra A, Shokrzadeh M, Naghshvar F, Salehi F, Ahmadi A. Melatonin ameliorates oxidative stress and reproductive toxicity induced by cyclophosphamide in male mice. Hum. Exp.Toxicol. 2014; 33: 185–195.
    • Kamdar BB, Tergas AI, Mateen FJ et al. Night-shift work and risk of breast cancer: a systematic review and meta-analysis. Breast Cancer Res Treat. 2013; 138, 1: 291–301.
    • Pshychenko VV, Cherno VS, Phrenkel DYu. Morphological and functional state of extraorganic bloodstream of pineal gland of rats under the chronic stress and illumination. Deutscher Wissenschaftsherold. 2016; 2: 3–5.
    • Reiter RJ, Rosales-Corral S, Tan DX et al. Melatonin as a mitochondria-targeted antioxidant: one of evolution’s best ideas. Cell. Mol. Life Sci. 2017; 74, 21: 3863–3881.
    • Sosa V, Moline T, Somoza R, Paciucci R, Kondoh H, et al. Oxidative stress and cancer: an overview. Ageing. Res. Rev. 2013; 12, 1: 376–390.
    • Suofu Y, Li W, Jean-Alphonse FG et al. Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release. Proc. Natl. Acad. Sci. USA. 2017; 114, 38: E7997–E8006.
    Publication of the article «World of Medicine and Biology» №2(76), 2021 year, 189-192 pages, index UDK 612.172:612.176:612.4:612.826.33:611.73
    DOI 10.26724/2079-8334-2021-2-76-189-192