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    О. D. Daniliv, Ye. V. Stetsuk, N. V. Boruta, G. V. Lukiantseva, V. I. Shepitko

    MORPHOLOGICAL FEATURES OF THE TRIGEMINAL GANGLION IN ACUTE ASEPTIC INFLAMMATION AT THE EARLY STAGES OF THE EXPERIMENT


    About the author: О. D. Daniliv, Ye. V. Stetsuk, N. V. Boruta, G. V. Lukiantseva, V. I. Shepitko
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation The phenomena of acute λ-carrageenan inflammation in the trigeminal ganglion were characterized by phasing. Thus, in the first stage, against the background of increasing hydration, minor destructive phenomena in the structure of the stroma of the trigeminal ganglion are revealed, which adversely affect metabolism, resulting in impaired blood circulation, reduced phagocytic response activity. Such changes are observed only in the early stages, which lead to slowing or suppression of the cell barrier formation, with subsequent reactivation and generalization of the process due to inflammatory factors activity in the trigeminal ganglion stroma and in the nervous tissue specifically. The second phase is characterized by regenerative phenomena; the products of tissue metabolism are resorbed or removed from the site of inflammation. All this occurs together with reducing the clinical signs of inflammation, normalization of biochemical and functional disorders that occur in the first phase of inflammation.
    Tags aseptic inflammation, λ-carrageenan, trigeminal ganglion, neurocyte, rats
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    Publication of the article «World of Medicine and Biology» №2(76), 2021 year, 207-210 pages, index UDK 591.483:599.35/.38
    DOI 10.26724/2079-8334-2021-2-76-207-210