About the author: |
I. V. Melnyk, S. L. Popel, E. Yo. Lapkovskiy, T. P. Vasylyk |
Heading |
EXPERIMENTAL MEDICINE |
Type of article |
Scentific article |
Annotation |
The study of histo-ultrastruction changes of different structural components of direct muscle of abdominal of sexually matured rats – males was a research purpose in the remote terms of ventral hernia and subsequent application of the physical loading of middle aerobic power. Light opticaly, electronical microscopical (for the exposure of structural transformations of muscle components) and histochemical (for determination of activity of succinate dehydrogenase after Nahlas – to identify muscular fibres with different phenotypes) methods at 55 sexually matured rats were studied structural track of adaptation of muscle compartmently at prolonged (240 days) ventral hernia and after 15-30 multiple physical loading of middle aerobic power in an ambassador post-operative period at alloplastic. It is shown that above all things, there are the changes of intramuscular network and morfometric changes blood vessels. These information closely correlate with the making progress changes of subcellular components of muscle fibers accountable for power and plastic balance. It is set that fast oxygen-glycolytics muscle fibers and their peripheral nervous vehicle are most sensible to the terms of prolonged ventral hernia. As a result of application of the physical loading of middle aerobic power the reparative regeneration is intensifyed, that substantially abbreviates the terms of renewal of structurally-functional properties of skeletal muscles in the conditions of ventral hernia illness. Thus, at ventral hernia the primary changes touch the sources of blood supply of abdominal muscles, with the secondary paranecrosis processes in muscle fibers and peripheral nervous vehicle with certain morfometric signs. |
Tags |
ventral hernia, muscle fibers, blood vessels, neuromuscular endings, physical loading |
Bibliography |
- Alekseeva T, Unger R, Brochhausen C. Engineering a micro-vascular capillary bed in a tissue-like collagen construct. Tissue Eng. 2014,20: 2656–2665.
- Barbosa E, Correia J, Ferreira F. Tratamien to de hernia ventral compleja contaminada en dos etapas. Revista HispanoAmericana de Hernia. 2017,5(2): 57 – 60. https://doi.org/10.20960/rhh.35
- Bosurgi L, Manfredi А, Rovere-Querini P. Macrophages in injured skeletal muscle: a perpetuum mobile causing and limiting fibrosis, prompting or restricting resolution and regeneration. Front. Immunol. 2011,5: 234–240.
- Ciciliot S, Schiaffino S. Regeneration of mammalian skeletal muscle. Basic mechanisms and clinical implications. Curr. Pharm. Des. 2010,16: 906–914.
- Faylona JM Evolution of ventral hernia repair. Asian Journal of Endoscopic Surgery. 2017,10(3): 252–258. https://doi.org/10.1111/ases.12392
- Hoppeler H, Mathieu O, Weibel ER, Krauer R, Lindstedt SL, Taylor CR. Design of the mammalian respiratory system. VIII. Capillaries in skeletal muscles. Respiration Physiology. 2011,44(1): 129–150. https://doi.org/10.1016/0034–5687(81)90080–3
- Kenneth M. Baldwin, Fadia Haddad The Evolution of Skeletal Muscle Plasticity in Response to Physical Activity and Inactivity. Muscle and Exercise Physiology. 2019;4: 347–377. https://doi.org/10.1016/b978–0–12–8145937.00016–5
- Latorfuna CL, Prinell F, Adorni F. Effect of mechanical and metabolic factors on motor function and fatique obesity in man and women. J Endocrinology Ivestigation. 2013;36(11): 1061–1068.. https://doi.org/10.1123/jab.16.1.98
- Lee SJ, Huynh TV, Lee VS, Sebald SM, Wilcox-Adelmann SA. Role of satellite cells versus myofibers in muscle atrophy induced by inhibition of the signaling pathway. Proceedengs of the National Academy of Sciences of the USA. 2012;109: 2353–2360. https://doi.org/10.1242/jeb.02182
- Liu G, MacGabhann F, Popel SL. Effects of Fiber Type and Size on the Heterogeneity of Oxygen Distribution in Exercising Skeletal Muscle. Engineering vascularized skeletal muscle tissue. Nat. Biotechnol. 2012,23: 879–884.
- Manyukov, VN, AA. Stadnikov, O M. Trubina, AD. Strekalovskaya Methods of research in biology and medicine. Orenburg state un-t. Orenburg: OSU, 2013 .—192р.
- Rossi А, Mammucari C, Argentini C, Reggiani C, Schiaffino S. Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles. The Journal of Physiology. 2010;588(2): 353–64. https://doi.org/10.1113/jphysiol.2009.181008
- Sakuma K, Wataru А, Yamaguchi A. The Intriguing Regulators of Muscle Mass in Sarcopenia and Muscular Dystrophy. Frontiers in Aging Neuroscience. 2014,29(6): 234 – 239. https://doi.org/10.3389 /fnagi. 2014.00230
- Schiaffino S, Reggiani C. Fiber Types in Mammalian Skeletal Muscles. Physiological Reviews. 2011,91(4):1447–1531. https://doi.org/10.1152/physrev.00031.2010
- Soldatov AA. The Diffusion Capacity of the Hematoparenchymal Barrier in Mammalian and Marine Fish Skeletal Muscles. Evolutionary Biochemistry and Physiology. 2018,54(1): 43–49. https://doi.org/10.1134/s0022093018010052
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Publication of the article |
«World of Medicine and Biology» №2(76), 2021 year, 227-232 pages, index UDK [611.7 3+616-00917]:976.015.572 |
DOI |
10.26724/2079-8334-2021-2-76-227-232 |