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    V. A. Turkina, N. Ye. Chemodurova, H. V. Pryzyglei, Y. B. Кuzminov

    POTENTIAL EMBRYOTOXIC EFFECT STUDY OF MINOXIDIL-CONTAINING LOTION IN EXPERIMENT WITH FEMALE RATS


    About the author: V. A. Turkina, N. Ye. Chemodurova, H. V. Pryzyglei, Y. B. Кuzminov
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation The purpose of this study was to establish maternal safety of topical preparation containing 5 % minoxidil, as well as safety for fetal development, fetus-maternal functional responses in experiments with laboratory rats using doses and methods of administration recommended by the manufacturer. Based on the results obtained under these experimental conditions, a lotion containing 5 % minoxidil does not cause changes to the reproductive system of rats and does not demonstrate embryotoxic effect.
    Tags minoxidil, androgenetic alopecia, embryotoxic effect
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    Publication of the article «World of Medicine and Biology» №2(76), 2021 year, 248-251 pages, index UDK 615.451.3.263.62:615.9:611.013.9
    DOI 10.26724/2079-8334-2021-2-76-248-251