English Українська
  • Main
  • Useful links
  • Information for Contributors
  • About
  • Editorial board

  • Article
    B. V. Hrytsuliak, V. B. Hrytsuliak, О. Ia. Hlodan, N. V. Bielova, N. P. Dolynko, T. V. Mykytyn

    CHANGES IN HEMODYNAMICS IN THE TESTES AND EJACULATES OF ADULT MEN IN CHRONIC DIABETES MELLITUS


    About the author: B. V. Hrytsuliak, V. B. Hrytsuliak, О. Ia. Hlodan, N. V. Bielova, N. P. Dolynko, T. V. Mykytyn
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation An analysis was performed of echometric, hemodynamic, histological and laboratory changes in the testes and ejaculate of infertile men aged 22–35 years (the first period of adulthood), who were diagnosed with insulin-dependent diabetes mellitus of moderate severity. It is established that under these conditions, the volume of both testicles probably decreases, hemodynamic parameters in them both within the spermatic cord and under the protein shell decrease, there is a reduction of spermatogenic epithelial cells’ layers in the vast majority of tortuous seminal tubules, the concentration of testosterone in the blood decreases, and in the ejaculate – the total number of sperm, the number of living and actively moving sperm reduces. The number of pathological forms of sperm doubles, and the number of immobile sperm increases by 5 times.
    Tags diabetes mellitus, testicles, hemodynamics, spermatogenesis
    Bibliography
    • Ametov AS, Kurochkyn YO, Zubkov AA. Sakharnyy dyabet i serdechno-sosudistye zabolevanyya. RMZh. 2014; 13:954. [in Russian] doi: 10.26442/20751753.2019.1.190273
    • Bezdetko PA. Epydemyolohyia y chastota sakharnoho dyabeta y dyabetycheskoi retynopatyy. Mezhdunarodnyi endokrynologicheskyi zhurnal. 2006; 4(6):37–45. [in Russian]
    • Blyshchak NB. Diabetychni angiopatiyi. Klinichna anatomiya i ta operatyvna khirurgiya. 2012;  11(2):74–77. [in Ukrainian] doi: 10.24061/1727–0847.11.2.2012.18
    • Dedov YY, Shestakova MV. Sakharnyy dyabet tipa 1: realii i perspektyvy. Meditsinskoe informatsionnoe agentstvo. 2016. 502 р. [in Russian]
    • Kyslyak OA, Myshlyaeva TO, Malysheva NV. Sakharnyy diabet 2 tipa, arterialnaya gipertenziya i risk serdechno-sosudistykh oslozhneniy. Sakharnyy diabet. 2008; 11(1):45–49. DOI: 10.14341/2072–0351–5945 [in Russian]
    • American Diabetes Association Standards of Medical Care in Diabetes. Diabetes Care. 2017. 142 р.
    • Bodnarchuk YuV. Morphological and functional changes and cluster characteristics of hepatocytes in immature rats with streptozotocin-induced diabetes. Deutscher Wissenschaftsherold. German Science Herald. 2016; 3:16–19.
    • IDF Diabetes Atlas-7 th Edition. 2016: [Еleсtronic resourse]. Mode access: http://www.diabetesatlas.org/#sthash.keNV3Uj4.
    • Pertseva NO, Chub DI, Gurzhiy OV. Double monitoring indices of arterial pressure and the lipid profile status in patients with diabetes mellitus 1 and 2 types depending on the glomerular filtration rate. World of Medicine and Biology. 2018; 3(65):103–110.
    • Pertseva NO, Chub DI, Gurzhiy OV. Glycosylated haemoglobin as a forecasting factor of progressing of diabetic nephropathy in patients with diabetes type 1. Medical perspectives. 2017; 22(4):32–39. DOI
    • Reutens AT. Epidemiology of diabetic kidney disease. Med Clin North Am. 2013 Jan; 97(1):1–18. DOI: 10.1016/j.mcna.2012.10.001.
    • Ritz E. Clinical manifestation and natural history of diabetic kidney disease. Med Clin North Am. 2013 Jan; 97(1):19–29. DOI: 10.1016/j.mcna.2012.10.008.
    Publication of the article «World of Medicine and Biology» №4(78), 2021 year, 036-040 pages, index UDK 616.681:616.697:612.616.379-008.67
    DOI 10.26724/2079-8334-2021-4-78-36-40