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    O. I. Makedonska, O. S. Voronkova, Yu. S. Voronkova, A. I. Vinnikov


    About the author: O. I. Makedonska, O. S. Voronkova, Yu. S. Voronkova, A. I. Vinnikov
    Type of article Scentific article
    Annotation Changes of microbiocenosis of different biotopes of the human body are known as dysbiosis. For the renovation of the composition of the microbiota, use the bacteriotherapeutic preparations – probiotics. The aim of the research was to study the effectiveness of the use of the mixed suspension of cells of probiotic strains Bacillus subtilis and Bacillus licheniformis for the correction of the composition of the microbiota of the vagina of white laboratory mice, induced by the intravaginal introduction of a biofilm forming strain of Staphylococcus aureus. It was shown that in cases of dysbiosis of genitourinary tract of mice, induced by the intravaginal introduction of a biofilm-forming strain of S. aureus, the use of probiotic microorganisms B. subtilis and B. licheniformis led to the tendency to normalization of the vaginal microbiota. Renovation of vaginal microbiome characterized by the increase of ratio anaerobic to anaerobic bacteria to 1: 71–1: 87 that in fact corresponded to normal index; the decrease of the frequency of determination and quantity of opportunistic bacteria, such as staphylococci and enterobacteria.
    Tags vaginal dysbiosis, microbiota, correction, probiotic, bacilli
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    Publication of the article «World of Medicine and Biology» №1(79), 2022 year, 209-213 pages, index UDK 579.61:579.861.2: 615.331
    DOI 10.26724/2079-8334-2022-1-79-209-213