| About the author: |
V. A. Filipenko, K. S. Poplavska, O. D. Karpinskaya, M. Yu. Karpinsky |
| Heading |
EXPERIMENTAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
There are bone defects that do not heal on their own, despite the ability of bone tissue to fully regenerate. These defects occur due to degenerative-dystrophic diseases, injuries, resections of tumors and tumor-like formations, metastatic lesions, as a result of the development of aseptic instability after primary arthroplasty. Autogenous material for transplantation is the most acceptable, but its use depends on the quality of the bone. Allografts have compensated for the shortcomings of autografts, but the risk of infection and ethical issues limit the use of this material. The group II cement that we offer retains the properties of tricalcium phosphate-based materials: high biocompatibility, osteoconductive and osteointegrative qualities, and, due to strengthening by HA whiskers, it has higher strength and slower biodegradation time. |
| Tags |
bioceramics, α-tricalcium phosphate, calcium phosphate cement, orthopedic surgery, bone regeneration |
| Bibliography |
- Zyman ZZ, Kaltsiyfosfatni biomaterialy.Navchalnyj posibnyk, 2018:285. [in Ukrainian]
- Kozlov, A.YU. Statisticheskiy analiz dannykh v MS Excel: Uchebnoe posobie. AYu Kozlov, VS Mhitaryan, VF Shishov. - Moskva: INFRA-M, 2021. - 320 c. [in Russian]
- Pankratov AS, Lekyshvyly MV, Kopetskyy̆ YS, Kostnaya plastika v stomatologii i cheliustno-lytsevoy̆ khirurgii. Osteoplastycheskye materyaly: rukovodstvo dlia vrachey. 2011 : 272. [in Russian]
- Tankut OV, Zamishchennia defektiv kistok pid chas totalnoho endoprotezuvannia kolinnoho suhloba (ohliad literatury). Ortopedyia, travmatologiya i protezirovanie. 2019; 3: 97–103. doi: 10.15674/0030-59872019397-103. [in Ukrainian]
- Filipenko VA, Vorontsov PM, Husak VS. Kistkova aloplastyka v razi reviziynoho endoprotezuvannia kulshovoho suhloba za umov aseptychnoi nestabilnosti atsetabuliarnoho komponenta. Ortopedyia, travmatolohyia y protezyrovanye. 2020; 4: 5–11. doi: 10.15674/0030-5987202045-11. [in Ukrainian]
- Bone grafts and substitutes market size, share and trends analysis report by material type (natural, synthetic), by application type (spinal fusion, craniomaxillofacial, long bone), by region, and segment forecasts, 2018–2025. [Online source]. 2018. Retrieved from https://www.grandviewre- search.com/industry-analysis/bone-grafts-substitutes-market
- Hashiguchi K, Yamakawa Y. Introduction to finite strain theory for continuum elasto-plasticity. Wiley: 2012; 417 p.
- Fillingham Y. Bone grafts and their substitutes. The Bone & Joint Journal. 2016; 98-B (1 Sup-pl A): 6–9. doi: 10.1302/0301-620X.98B.36350.
- Laurencin C, Khan Y, El-Amin SF, Bone graft substitutes. Expert review of medical devices. 2006; 3 (1): 49–57. doi: 10.1586/17434440.3.1.49.
- Sohn HS, Review of bone graft and bone substitutes with an emphasis on fracture surgeries. 2019; 23: Article ID : 9. doi: 10.1186/s40824-019-0157-y.
- Tovar N, Gimbo R, Gangolli R, Witek l, Lorenzoni F, Marin C, et al. Modification of xenogeneic graft materials for improved release of p-15 peptides in a calvarium defect model. J Craniofac Surg. 2014; 25(1):70–76. doi: 10.1097/ScS.0b013e3182a2dfe7.
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| Publication of the article |
«World of Medicine and Biology» №1(79), 2022 year, 227-231 pages, index UDK 616.71-089.843 / .844: 615.461] 048.8 |
| DOI |
10.26724/2079-8334-2022-1-79-227-231 |
