| About the author: |
O. M. Bilovol, I. I. Kniazkova, O. M. Kirienko, N. V. Kuzminova, V. O. Golovachova, D. O. Kirienko, L. P. Abramova |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The purpose of the study was to clarify the diagnostic significance of neutrophil gelatinase-associated lipocalin and cystatin C in the blood of patients with arterial hypertension and type 2 diabetes mellitus and their correlation with intrarenal hemodynamic parameters. It was installed that in comparison with persons without diabetes in patients with arterial hypertension and type 2 diabetes mellitus at the stage of preclinical kidney damage found a more significant increase in neutrophil gelatinase-associated lipocalin and cystatin C in the blood. This allows us to consider these indicators as diagnostic manifestations of early detection of diabetic nephropathy. It was determined that a significant decrease in the final diastolic arterial blood flow velocities and a significant increase in the resistance index are diagnostic markers of morpho-functional changes in the kidneys during duplex scanning of the renal arteries in patients with arterial hypertension and type 2 diabetes mellitus. |
| Tags |
neutrophil gelatinase-associated lipocalin, cystatin C, duplex scanning of renal arteries, arterial hypertension, type 2 diabetes mellitus |
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| Publication of the article |
«World of Medicine and Biology» №2(80), 2022 year, 024-029 pages, index UDK 616.61-008.6-07:[616.12-008.331.1+616.379-008.64] |
| DOI |
10.26724/2079-8334-2022-2-80-24-29 |
