| About the author: |
O. V. Dienha, N. V. Malekh, O. A. Makarenko, T. O. Pyndus, A. Jenča, S. A. Shnaider |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The study is dedicated to assessing the impact of the developed treatment-and-prophylactic complex on the biochemical parameters of the oral fluid of children with hypertrophic gingivitis. The study involved 30 children aged 13–16 years with a diagnosis of hypertrophic gingivitis. The conducted studies testify to the rather high efficiency of the proposed treatment-and-prophylactic therapy for children with hypertrophic gingivitis, which included a universal natural biological complex of drugs with a broad therapeutic and prophylactic effect. The developed therapeutic and prophylactic complex helped to normalize the biochemical parameters of oral fluid in children, improving antioxidant protection, reducing the intensity of inflammation, the degree of lipid peroxidation, the level of contamination of the oral cavity and increasing non-specific antimicrobial protection. |
| Tags |
children, periodontal tissue diseases, dental disease, biochemical markers, oral fluid |
| Bibliography |
- Abbasova RA, Amiraliyev RS, Zeynalov GA. Kratkiy obzor sovremennykh metodov profilaktiki yunosheskogo gingivita. Problemy sovremennoy nauki i obrazovaniya. 2021; 3:38–42. [in Russian]
- Kamilov KH, Takhirova K, Saidova N, Makhmudova N. Gipertroficheskiy gingivit u podrostkov: osobennosti klinicheskikh proyavleniy, metody diagnostiki i lecheniya. Stomatologiya. 2020;1(78):65–69. DOI: 10.34920/2091-5845-2020-18 [in Russian]
- Levitskiy AP. Primeneniye antidisbioticheskikh sredstv v stomatologii. Vssnik stomatologii. 2014;4(89):89–92. [in Russian]
- Levitsky AP, Stefanov AV. Metody opredeleniya aktivnosti elastazy i yeye ingibitorov: metod. rekomendatsii. Kiev, GFK, 2002:15. [in Russian]
- Mamaev OV, Tsinekker DA. Uroven gormonov gipofiza i polovykh zhelez u podrostkov s khronicheskim gipertroficheskim gingivitom. Vestnik sovremennoy klinicheskoy meditsiny. 2014; 2:21–24. [in Russian]
- Bostanci N, Mitsakakis K, Afacan B, Bao K, Johannsen B, Baumgartner D, et al. Validation and verification of predictive salivary biomarkers for oral health. Sci Rep. 2021; 11(1):6406. DOI: 10.1038/s41598-021-85120-w.
- Chapple IL, Bouchard P, Cagetti MG, Campus G, Carra MC, Cocco F, et al. Interaction of lifestyle, behaviour or systemic diseases with dental caries and periodontal diseases: consensus report of group 2 of the joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases. J Clin Periodontol. 2017; 44(18):S39–S51. DOI: 10.1111/jcpe.12685.
- Jensen E, Allen G, Bednarz J, Couper J, Peña A. Periodontal risk markers in children and adolescents with type 1 diabetes: A systematic review and meta-analysis. Diabetes Metab Res Rev. 2021; 37(1):e3368. DOI: 10.1002/dmrr.3368
- Kaczor-Urbanowicz KE, Martin Carreras-Presas C, Aro K, Tu M, Garcia-Godoy F, Wong DT. Saliva diagnostics - Current views and directions. Exp Biol Med (Maywood). 2017; 242(5):459–472. DOI: 10.1177/1535370216681550.
- Kaskova LF, Popyk KM, Ulasevych LP. Physical indices of oral fluid in children of school age with different dental status. World of Medicine and Biology. 2019; 4(70):091–094. DOI: 10.26724/2079-8334-2019-4-70-91-94
- Kassebaum NJ, Smith AGC, Bernabé E, Fleming TD, Reynolds AE, Vos T, et al. Global, Regional, and National Prevalence, Incidence, and Disability-Adjusted Life Years for Oral Conditions for 195 Countries, 1990-2015: A Systematic Analysis for the Global Burden of Diseases, Injuries, and Risk Factors. J Dent Res. 2017 Apr; 96(4):380–387. DOI: 10.1177/0022034517693566
- Kc S, Wang XZ, Gallagher JE. Diagnostic sensitivity and specificity of host-derived salivary biomarkers in periodontal disease amongst adults: Systematic review. J Clin Periodontol. 2020; 47(3):289–308. DOI: 10.1111/jcpe.13218.
- Murakami S, Mealey BL, Mariotti A, Chapple ILC. Dental plaque-induced gingival conditions. J Clin Periodontol. 2018; 89(1):S17–S27. DOI: 10.1002/JPER.17-0095.
- Nowicki EM, Shroff R, Singleton JA, Renaud DE, Wallace D, Drury J, et al. Microbiota and Metatranscriptome Changes Accompanying the Onset of Gingivitis. mBio. 2018; 9(2):e00575–18. DOI: 10.1128/mBio.00575-18.
- Rathee M, Jain P. Gingivitis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022:1–6.
|
| Publication of the article |
«World of Medicine and Biology» №2(80), 2022 year, 060-064 pages, index UDK [616-053.4+616.316-008.8]:616.311.2-002 |
| DOI |
10.26724/2079-8334-2022-2-80-60-64 |
