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    R. A. Safonov, V. Yu. Prokopiuk, O. V. Prokopiuk, V. V. Lazurenko, O. M. Tishchenko, O. B. Ovcharenko

    COMPARISON OF THE EFFECT OF DIFFERENT MESH IMPLANTS ON THE REPRODUCTIVE SYSTEM IN EXPERIMENTAL MODELS OF GYNECOLOGICAL SURGERIES


    About the author: R. A. Safonov, V. Yu. Prokopiuk, O. V. Prokopiuk, V. V. Lazurenko, O. M. Tishchenko, O. B. Ovcharenko
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation Genital prolapse complicates the lives of many women after the age of 50. The use of mesh implants is a promising method of surgical correction of this disease. The study on mice compared the effect of the most common surgical meshes on the morphofunctional state of the reproductive system of animals, the postoperative period, and the completeness of morphological and functional recovery of the defects in the lower abdominal wall. It was found that thinner meshes cause less inflammatory reactions, faster recovery and less atrophic phenomena in the internal genitals. The recovery rate also depends on the material and structure of the mesh.
    Tags gynecological surgeries, surgical meshes, genital prolapse, uterus, ovaries
    Bibliography
    • Yeroshenko GA, Fedonyuk LYa. Morfolohichni zminy tkanyn perednoyi cherevnoyi stinky shchuriv pislia implantatsii aloplastychnoho materialu, obroblenoho kolahenom. Morfolohiya. 2017; 11(2):19–24. [in Ukrainian]
    • Kryschuk MH, Lysenko RB. Biomekhanika perednoyi cherevnoyi stinky liudyny z implantatamy pry funktsionalnykh navantazhenniakh. Visnyk natsionalnoho tekhnichnoho universytetu Ukrayiny “Kyivskyi politekhnichnyi instytut”. Seriya mashynobuduvannia. 2014;3(72):201–207. [in Ukrainian]
    • Pelypenko OV, Shepitko VI, Pelypenko LB. Osoblyvosti prostorovoyi orhanizatsiyi suhlobovoho khriaschu kolinnoho suhlobu. Svit medytsyny ta biolohiyi. 2018; 4 (66): 188–190. doi: 10.26724/2079-8334-4-66-188-190 [in Ukrainian]
    • Chanda A, Ruchti T, Upchurch W. Biomechanical modeling of prosthetic mesh and human tissue surrogate interaction. Biomimetics (Basel). 2018; 18(3): E27. doi: 10.3390/biomimetics3030027
    • Curry A, Williams T, Penny ML. Pelvic Inflammatory Disease: Diagnosis, Management, and Prevention. Am Fam Physician. 2019;100(6):357–64. PMID: 31524362
    • Kowalik CR, Lakeman MME , de Kraker AT , Roovers JPWR. Effects of mesh-related complications in vaginal surgery on quality of life. Int Urogynecol J. 2019;30(7):1083–9. doi: 10.1007/s00192-018-3680-9
    • Lu Y, Fu S, Zhou S, Chen G, Zhu C, Li N,et al. Preparation and biocompatibility evaluation of polypropylene mesh coated with electrospinning membrane for pelvic defects repair. J Mech Behav Biomed Mater. 2018; 81:142–8. doi: 10.1016/j.jmbbm.2018.02.030
    • Mateu AL, Errando SC, Gutierrez Ruiz C, Araño P, Palou Redorta J. Pelvic organ prolapse repair with mesh: mid-term efficacy and complications. Urol Int. 2018;101(2):201–5. doi: 10.1159/000489636
    • Marcu D, Diaconu C, Iorga L, Bratu O, Mischianu D. Mesh colposacropexy in the management of anterior vaginal compartment prolapse. J Med Life. 2019;12(1):65–70. doi: 10.25122/jml-2019-0018. PMID: 31123527; PMCID: PMC6527416
    • Mohsina A, Kumar N, Sharma AK, Shrivastava S, Mathew DD, Remya V, et al. Polypropylene mesh seeded with fibroblasts: A new approach for the repair of abdominal wall defects in rats. Tissue Cell. 2017;49(3):383–92. doi: 10.1016/j.tice.2017.04.004
    • Nager CW, Visco AG, Richter HE, Rardin CR, Rogers RG, Harvie HS, et al. Effect of Vaginal Mesh Hysteropexy vs Vaginal Hysterectomy With Uterosacral Ligament Suspension on Treatment Failure in Women With Uterovaginal Prolapse: A Randomized Clinical Trial. JAMA. 2019;322(11):1054–65. doi: 10.1001/jama.2019.12812
    • Noé GK. Genital Prolapse Surgery: What Options Do We Have in the Age of Mesh Issues? J Clin Med. 2021;10(2):267. doi: 10.3390/jcm10020267 12
    • Onwude JL. Genital prolapse in women. BMJ Clin Evid. 2012;2012:0817. PMID: 22414610.
    • Qiu W, Zhong C, Xu R, Zou T, Wang F, Fan Y, et al. Novel large-pore lightweight polypropylene mesh has better biocompatibility for rat model of hernia. J Biomed Mater Res A. 2018;106(5):1269–75. doi: 10.1002/jbm.a.36326
    • Wiessner R, Kleber T, Ekwelle N, Ludwig K, Richter DU. In-vitro examination of the biocompatibility of fibroblast cell lines on alloplastic meshes and sterilized polyester mosquito mesh. Hernia. 2017; 21(3):407–16. doi: 10.1007/s10029-016-1550-2
    Publication of the article «World of Medicine and Biology» №2(80), 2022 year, 227-231 pages, index UDK 618-7:57.085.23
    DOI 10.26724/2079-8334-2022-2-80-227-231