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    G. A. Аkhmadov

    EARLY MARKERS OF DIABETIC NEPHROPATHY IN CHILDREN WITH TYPE 1 DIABETES MELLITUS


    About the author: G. A. Аkhmadov
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation The purpose of the study was to reveal the markers for timely detection of diabetic nephropathy in children with type 1 diabetes mellitus. 54 children with type 1 diabetes mellitus were examined (mean age: 13.76±4.5 years; diseases duration: 5.68±3.7 years). Blood glucose, glycohemoglobin, blood urea, general analysis of urine, calcium, creatinine, protein, glucose in the urine and microalbuminuria were determined by laboratory tests. Conditions of kidney and liver were access by abdomen ultrasound. Results showed that in children with type 1 diabetes mellitus there was a positive correlation between microalbuminuria and disease duration (r=+0.383, p=0.036), urine glucose and the width of the right (r=+0.82, p<0.05) and left kidney (r=+0.82, p<0.05), thickening of the parenchyma (r=+0.84, p<0.05) and microalbuminuria (r=+0.87, p<0.05). According to the result of our study we recommend systematic monitoring of microalbuminuria and other informative affecting indicators to prevent progression toward diabetic nephropathy in children with type 1 diabetes mellitus.
    Tags type 1 diabetes mellitus,diabetic kidney disease,microalbuminuria,risk factors
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    Publication of the article «World of Medicine and Biology» №3(81), 2022 year, 013-017 pages, index UDK 616.379-008.64; 616.4-092
    DOI 10.26724/2079-8334-2022-3-81-13-17