| About the author: |
I. S. Lembryk, A. B. Volosianko, O. O. Tsytsiura, I. V. Shlimkevych, O. V. Zhyliak, P. Z. Buiak, A. B. Stefanyshyn |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
Oxidative stress plays a major role in the development of metabolic renal diseases in children. We established the pediatric renal microlithiasis course in the setting of disorders of lipid peroxidation. 176 children aged 1 to 18 years were examined who were diagnosed with renal microlithiasis and were out-patients and in-patients in the Regional Children Counselling Outpatient Clinic and Nephrology Department of the Public Nonprofit Enterprise “Ivano-Frankivsk Regional Children`s Clinical Hospital of Ivano-Frankivsk Oblast Council” during the period of 2016 till 2019. Most commonly, in children the diagnosis of oxaluria (34.1 %) and oxalate-calcium nephropathy (30.1 %) was verified. Based on gender, girls prevail over boys (75.0 % and 25.0 %, р<0.05). It is established that pediatric renal microlithiasis occurs more commonly at the age of 13–17 years. The increase of primary lipid peroxidation product activity (diene conjugates) in the blood of sick children is evidence of activation of free radical processes in renal microlithiasis. The average rate of nitrites is significantly lower in children aged 13–17 years with phosphaturia (37.11 and 41.30 mol/L, p <0.01). In elder children this index does not change compared to norm. |
| Tags |
disease progression,children,nephrolithiasis,kidney calculi,oxidative stress,diagnosis |
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| Publication of the article |
«World of Medicine and Biology» №3(81), 2022 year, 094-098 pages, index UDK 616-039.3+616.61+612.176 |
| DOI |
10.26724/2079-8334-2022-3-81-94-98 |
