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    S. O. Kramarov, I. Yu. Seriakova, V. V. Yevtushenko, I. V. Shpak, V. O. Shadrin, V. O. Doroshenko, N. S. Kyrytsia

    CLINICAL CHARACTERISTICS OF COVID-19 IN CHILDREN OF DIFFERENT AGE GROUPS


    About the author: S. O. Kramarov, I. Yu. Seriakova, V. V. Yevtushenko, I. V. Shpak, V. O. Shadrin, V. O. Doroshenko, N. S. Kyrytsia
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation The study is devoted to accessing the clinical and epidemiological features of the coronavirus infection in children of different ages who were hospitalized during the 2020–2021 outbreaks of the epidemic. A retrospective analysis of 530 case histories of children under the age of 18 with coronavirus infection was conducted. The study revealed the predominance of general infectious symptoms and manifestations of upper respiratory tract lesions in children of all ages. A more severe course of the disease was registered in older children and was associated with the lower respiratory tract involvement. Children aged 1 month had relatively lower risks of lower respiratory tract injury compared to other age groups. We also found relatively higher levels of leukocytes, platelets and procalcitonin in children of this age.
    Tags coronavirus infection,children,clinical picture,epidemic
    Bibliography
    • Avetikov DS, Ananieva MM, Loban GA, Faustova MO, Skikevych M G, Chumak YuV, et al. The profile of specific antibodies to Sars-Cov-2 in residents of the central and eastern regions of Ukraine.World of Medicine and Biology.1(79), 2022: 11-15. doi: 10.26724/2079-8334-2022-1-79-11-15
    • Bo Z, Yuan Y, Wang S, Zhang Z, Yang M, Deng X. et al. Risk profiles of severe illness in children with COVID-19: a meta-analysis of individual patients. Pediatr Res. 2021 Aug;90(2):347-352. doi: 10.1038/s41390-021-01429-2
    • Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet.2020 Mar 7;395(10226):809-815. doi:10.1016/S0140-6736(20)30360-3
    • Dewi R, Kaswandani N, Karyanti MR, Setyanto DB, Pudjiadi AH, Hendarto A, et al. Mortality in children with positive SARS-CoV-2 polymerase chain reaction test: Lessons learned from a tertiary referral hospital in Indonesia. Int J Infect Dis.2021Jun;107:78-85. doi:10.1016/j.ijid.2021.04.019.
    • Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 Among Children in China. Pediatrics June 2020, 145(6):e20200702. doi: 10.1542/peds.2020-0702
    • Götzinger F, Santiago-García B, Noguera-Julián A, Lanaspa M, Lancella L, Calò Carducci FI, et al. COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study. Lancet Child Adolesc Health 2020 Sep;4(9):653-661. doi: 10.1016/S2352-4642(20)30177-2
    • Kainth MK, Goenka PK, Williamson KA, Fishbein JS, Subramony A, Schleien C, et al. Early experience of COVID-19 in a US children’s hospital. Pediatrics. 2020; doi: 10.1542/peds.2020-003186.
    • Ludvigsson J. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Pediatr. 2020 Jun;109(6):1088-1095. doi: 10.1111/apa.15270
    • Preston LE, Chevinsky JR, Kompaniyets L, Lavery AM, Kimball A, Boehmer TK, et al. Characteristics and Disease Severity of US Children and Adolescents Diagnosed With COVID-19. JAMA Netw Open. 2021 Apr; 4(4): e215298. doi:  0.1001/jamanetworkopen.2021.5298
    • Raschetti R, Vivanti A, Vauloup C, Loi B, Benachi A, De Luca D. Neonatal SARS-CoV-2 infections: systematic review, synthesis and meta-analysis of reported cases. Nature Communications volume 11, Article number: 5164 (2020).
    • Tagarro A, Epalza C, Santos M, Sanz-Santaeufemia F, Otheo E, Moraleda C, Calvo C. Screening and severity of Coronavirus Disease 2019 (COVID-19) in children in Madrid, Spain. JAMA Pediatrics.2021;175(3):316-317. doi: 10.1001/jamapediatrics.2020.1346
    • Tezer H, Bedir Demirdag T. Novel coronavirus disease in children. Turk J Med Sci. (2020) 50:592–603 doi: 10.3906/sag-2004-174.
    • Tsankov BK, Allaire JM, Irvine MA, Lopez AA , Sauvé LJ, Vallance BA, et al. Severe COVID-19 Infection and Pediatric Comorbidities: A Systematic Review and Meta-Analysis International Journal of Infectious Diseases, 103, 246–256.https:/ /doi.org/10.1016/j.ijid.2020.11.163
    • Yasuhara J, Kuno T, Takagi H, Sumitomo N. Clinical characteristics of COVID-19 in children: A systematic review. Pediatric Pulmonology. 2020;55:2565–2575. doi:10.1002/ppul.24991
    Publication of the article «World of Medicine and Biology» №4(82), 2022 year, 101-106 pages, index UDK 616.9-02:578.834
    DOI 10.26724/2079-8334-2022-4-82-101-106