| About the author: |
Y. O. Yemchenko, I. P. Kaydashev, K. Ye. Ishcheykin, O. V. Bezeha, K. V. Vasylyeva, Ya. O. Oliinichenko, H. Yu. Morokhovets |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The recent increase in cases of comorbidity of psoriasis and obesity leads to severe, atypical, disabling, and therapy-resistant forms of dermatosis, significantly worsen the quality of life of patients, reduces work capacity and social activity of patients, which determines not only the medical but also the social significance of the problem. There is a theoretical rationale for the possible role of circadian rhythm disturbances, manifested by a change in eating behavior, a decrease in sleep duration, and the individual chronotype of patients in developing obesity and some autoimmune diseases. However, this issue remains insufficiently studied and proven. The purpose of our study was to identify the correlation between the circadian rhythm and indicators of changes in the chronotype of a person's working capacity and indicators of the severity of the course of psoriatic disease, the degree of obesity, and the degree of the negative impact of the disease on the quality of life of patients. The results of the correlation analysis showed a very high negative correlation between the chronotype of patients' working capacity and BMI indicators and a high negative correlation between the indicators of the PASI index, ACTIVITY, and the chronotype of patients' working capacity. |
| Tags |
psoriasis,alimentary obesity,сhronotype,quality of life |
| Bibliography |
- Yemchenko YaO. Rol PPAR v patohenezi psoriazu ta ozhyrinnia. Aktualni problemy suchasnoyi medytsyny: Visnyk ukrainskoyi medychnoyi stomatolohichnoyi akademiyi. 2019; 2(66):81–85. DOI 10.31718/2077-1096.19.2.224 [in Ukrainian].
- Yemchenko YaO, Ishcheikin KYe, Kaidashev IP. Aspekty formuvannia personifikovanoho pidkhodu do likuvannia komorbidnosti psoriatychnoyi khvoroby. Ozhyrinnia. Aktualni problemy suchasnoyi medytsyny: Visnyk ukrainskoyi medychnoyi stomatolohichnoyi akademiyi. 2019; 2(151):34–38. DOI 10.29254/2077-4214-2019-2-2-151-34-38. [in Ukrainian].
- Nevoit GV, Potiazhenko MM, Mintser OP. Systemni zalezhnosti zmin skladu tila pry prohresuvanni neinfektsiinykh zakhvoriuvan. Svit medytsyny ta biolohiyi. 2021; 3(77):132–137. DOI 10.26724/2079-8334-2021-3-77-132-137 [in Ukrainian].
- Alonso-Vale MI, Peres SB, Vernochet C, Farmer SR, Lima FB. Adipocyte differentiation is inhibited by melatonin through the regulation of C/EBPbeta transcriptional activity. J Pineal Res. 2019; 47(3):221–7. doi: 10.1111/j.1600-079X.2009.00705. x.
- Basra MK, Fenech R, Gatt RM, Salek MS, Finlay AY. The Dermatology Life Quality Index 1994-2007: a comprehensive review of validation data and clinical results. Br J Dermatol. 2018; 159(5):997–1035. doi: 10.1111/j.1365-2133.2008.08832. x.
- Colles SL, Dixon JB, O’Brien PE. Night eating syndrome and nocturnal snacking: association with obesity, binge eating and psychological distress. Int J Obes (Lond). 2017; 31:1722-1730. DOI:10.1038/sj.ijo.0803664.
- Dаrеskауа МА, Rychkova LV, Kolesnikov SI, Gavrilova OA, Kravtsova OV, Grebenkina LA, et al. Oxidative stress parameters in adolescent boys with exogenous-constitutional obesity. Free Radic Biol Med. 2017; 112(1): 129–130.
- De Bacquer D, Van Risseghem M, Clays E, Kittel F, De Backer G, Braeckman L. Rotating shift work and the metabolic syndrome: a prospective study. Int J Epidemiol. 2019; 38(3):848–54. doi: 10.1093/ije/dyn360.
- Ford ES, Li C, Wheaton AG, Chapman DP, Perry GS, Croft JB. Sleep duration and body mass index and waist circumference among U.S. adults. Obesity (Silver Spring). 2019; 22(2):598–607. doi: 10.1002/oby.20558.
- Garaulet M, Gómez-Abellán P, Alburquerque-Béjar JJ, Lee YC, Ordovás JM, Scheer FA. Timing of food intake predicts weight loss effectiveness. Int J Obes (Lond). 2018; 37(4):604–11. doi: 10.1038/ijo.2012.229.
- Garaulet M, Madrid JA. Chronobiological aspects of nutrition, metabolic syndrome and obesity. Adv Drug Deliv Rev. 2018; 62(9-10):967-78. doi: 10.1016/j.addr.2010.05.005.
- National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI). The practical guide: identification, evaluation, and treatment of overweight and obesity in adults. Bethesda: National Institutes of Health. 2000, NIH publication 00-4084.
- Salgado-Delgado R, Angeles-Castellanos M, Saderi N, Buijs RM, Escobar C. Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work. Endocrinology. 2019; (3):1019–29. doi: 10.1210/en.2009-0864.
- Szosland D. Shift work and metabolic syndrome, diabetes mellitus and ischaemic heart disease. Int J Occup Med Environ Health. 2020; 23(3):287–91. doi: 10.2478/v10001-010-0032-5.
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| Publication of the article |
«World of Medicine and Biology» №1(83), 2023 year, 068-072 pages, index UDK 616.12-008:616.517-056.5 |
| DOI |
10.26724/2079-8334-2023-1-83-68-72 |
