| About the author: |
H. M. Aliyeva, H. A. Kadirova, N. H. Mammadova, R. S. Bairamova, H. T. Mansurova, G. C. Mehdiyeva, N. A. Mukhtarova |
| Heading |
EXPERIMENTAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The purpose of the study was to assess the antimicrobial effect of essential oil obtained from the Satureja hortensis L plant grown in Azerbaijan. The qualitative composition and content (mg/kg) of Satureja hortensis L essential oil was determined by chromatography-mass spectrometry. Antimicrobial effect of Satureja hortensis L essential oil against microbial cultures is determined by disk-diffusion method. According to the results, the essential oil isolated from Satureja hortensis, both in native form and in dilutions, had a detrimental effect on the test cultures of S.aureus, E.coli, K.pneumoniae, H.pylori and P.aeruginosa, C.albicans, causing a complete or partial delay in their growth. The results obtained give grounds to assume that the synthesized essential oil of Satureja hortensis has a high antimicrobial effect. Therefore, this herbal preparation can be used in the future in the preparation of new drugs in the treatment of infectious diseases caused by these microorganisms. |
| Tags |
Satureja hortensis L extract,chromato-mass spectrometry,serial dilution method,disk diffusion method,antimicrobial |
| Bibliography |
- Adams RP. Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry, 5th Ed. (online). Biology Department Baylor University Texensis Publishing Gruver, TX USA 2017, 698 p.
- Adel FA, Mengjin S, Cunyu L, Wenyi K. Comparative analysis of antioxidant activities of essential oils and extracts of fennel (Foeniculum vulgare Mill.) seed from Egypt and China. Food Sci Hum Wellness. 2019; 8: 67–72.
- Alizade VM, Shulkina T. The flora of Azerbaijan for the world horticulture. Plant & Fungal Research. 2018; 1(1): 2–8. December 2018. http://dx.doi.org/10.29228/plantfungalres.
- Asadipour M, Amirghofran Z. Satureja hortensis induces cell death and inhibited cell cycle progression in K562 myelogenous and Jurkat T cell leukemia cell lines. J Immunoassay Immunochem. 2019;40(5):459–472. doi: 10.1080/15321819.2019.1629592.
- Bakhshaliyeva KF, Asgerli LX, Safarova ASh. General characteristics of new and some rare species of Azerbaijan mycobiota. Int. J. Adv. Res. Biol. Sci. 2019; 6(4): 139–148.
- Bobrova NA, Vazhnichaya EM, Loban GA, Devyatkina TA, Lugovaya LA. Balyuk OYe, et al. Evaluation of susceptibility of reference strains of microorganisms to the combined action of essential oils and mexidol. World of medicine and biology. 2021; 2 (76): 173–178. doi: 10.26724/2079-8334-2021-2-76-173-178.
- Ejaz A, Waliat S, Arshad MS, Khalid W, Khalid MZ, Rasul Suleria HA, et al. comprehensive review of summer savory (Satureja hortensis L.): promising ingredient for production of functional foods. Front Pharmacol. 2023 Jul 24;14:1198970. doi: 10.3389/fphar.2023.1198970.
- Emre İ, Kurşat M, Yilmaz Ö, Erecevit P. Chemical compositions, radical scavenging capacities and antimicrobial activities in seeds of Satureja hortensis L. and Mentha spicata L. subsp. spicata from Turkey. Braz J Biol. 2021 Jan-Feb;81(1):144–153. doi: 10.1590/1519-6984.224654.
- Fierascu I, Dinu-Pirvu CE, Fierascu RC, Velescu BS, Anuta V, Ortan A, et al. Phytochemical Profile and Biological Activities of Satureja hortensis L.: A Review of the Last Decade. Molecules. 2018 Sep 25;23(10):2458. doi: 10.3390/molecules23102458.
- Hagh LG, Arefian A, Farajzade A, Dibazar S, Samiea N. The antibacterial activity of “Satureja hortensis” extract and essential oil against oral bacteria. Dent Res J (Isfahan). 2019 May-Jun;16(3):153–159.
- Ibrahimova A, Alizade V, Mehdiyeva NP, Kerimov V. Plants of the Greater Caucasus (Azerbaijan). January 2019. Publisher: RedN Line. Editor: Thomas Borsch. 351 p. ISBN: 978-9952-414-10-3.
- Jalilova SKh, Ismayilova GE, Bayramova FV. The Fungicide Feature of Some Essential Oil Plants used in the Folk Medicine. Int.J.Curr.Microbiol.App.Sci. 2019; 8(06): 574–578.
- Mammadova HG, Serkerov SV, Alasgarova AN. Investigation of Biologically Active Substances Obtained from Johrenia paucijuga (DC) of the Species Bornm. Jplant Biochem Physiol. 2018; (5): 209.
- Mašković P, Veličković V, Mitić M, Đurović S, Zeković Z, Radojković M, et al. (2017). Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity. Industrial Crops Prod. 109, 875–881. 10.1016/j.indcrop.2017.09.063.
- Weinstein MP, Lewis JS 2nd. The Clinical and Laboratory Standards Institute Subcommittee on Antimicrobial Susceptibility Testing: Background, Organization, Functions, and Processes. J Clin Microbiol. 2020 Feb 24;58(3):e01864–19. doi: 10.1128/JCM.01864-19.
|
| Publication of the article |
«World of Medicine and Biology» №4(90), 2024 year, 158-162 pages, index UDK 615.322: 547.913 |
| DOI |
10.26724/2079-8334-2024-4-90-158-162 |