| About the author: |
R. R. Aliyev, Sh. N. Mehtiyeva, R. K. Shiraliyeva |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The purpose of this article was to study the incidence rate of Multiple Sclerosis (MS) in the northern areas of Azerbaijan, specifically the Sheki-Zagatala and Guba-Khachmaz economic regions, over the study period from January 1, 2013, to December 31, 2022. A total of 181 patients were confirmed with MS, with an average diagnostic age of 35.25±8.85 years and a female-to-male ratio of 1.62:1. The average age at the probable first MS attack was 29.57±8.59 years, with a diagnostic delay averaging 5.67±4.05 years. The most common type of MS was relapsing-remitting MS, observed in 82.87% of cases. Secondary-progressive MS was identified in 9.94% of patients. Over the 10-year study period, the average incidence of MS was 1.58±0.37 per 100,000 population, with rates of 1.96±0.57 per 100,000 in women and 1.20±0.45 per 100,000 in men. The average incidence in rural areas was 1.17±0.38 per 100,000, and in urban areas, it was 2.51±0.82 per 100,000. |
| Tags |
Azerbaijan,multiple sclerosis,epidemiology,incidence,population |
| Bibliography |
- Biernacki T, Sandi D, Fricska-Nagy Z, Kincses ZT, Füvesi J, Laczkó R, et al. Epidemiology of multiple sclerosis in Central Europe, update from Hungary. Brain Behav. 2020 May;10(5):e01598. doi: 10.1002/brb3.1598.
- Bölük C, Türk Börü U, Taşdemir M, Gezer T. Epidemiology of Multiple Sclerosis in Turkey; A Ten-Year Trend in Rural Cities. Turk J Neurol 2021;27:41-45 DOI:10.4274/tnd.2020.36418.
- Botchorishvili N, Shiukashvili N, Mikeladze N, Dzagnidze A, Mikava N, Tighashvili M, et al. Screening of Cognitive Impairment in Patients with Multiple Sclerosis: A Cross-Sectional Study in Georgia. Neurol Res Int. 2021 May 27;2021:5591078. doi: 10.1155/2021/5591078.
- Boyko A, Melnikov M. Prevalence and Incidence of Multiple Sclerosis in RF: 30 Years of Studies. Brain Sci. 2020 May 18;10(5):305. doi: 10.3390/brainsci10050305.
- Daltrozzo T, Hapfelmeier A, Donnachie E, Schneider A, Hemmer B. A Systematic Assessment of Prevalence, Incidence and Regional Distribution of Multiple Sclerosis in Bavaria From 2006 to 2015. Front Neurol. 2018 Oct 30;9:871. doi: 10.3389/fneur.2018.00871.
- Demographic indicators of Azerbaijan. Statistical publication. 2023. Official Publication. State Statistical Committee of the Republic of Azerbaijan. Baku, Çaşıoğlu Eİ-MMC. 2023. 590 p.
- Dobson R, Giovannoni G. Multiple sclerosis – a review. Eur J Neurol. 2019 Jan;26(1):27-40. doi: 10.1111/ene.13819.
- Flemmen HØ, Simonsen CS, Berg-Hansen P, Moen SM, Kersten H, Heldal K, et al. Prevalence of multiple sclerosis in rural and urban districts in Telemark county, Norway. Mult Scler Relat Disord. 2020 Oct;45:102352. doi: 10.1016/j.msard.2020.102352.
- Ford H. Clinical presentation and diagnosis of multiple sclerosis. Clin Med (Lond). 2020 Jul;20(4):380-383. doi: 10.7861/clinmed.2020-0292.
- GBD 2016 Multiple Sclerosis Collaborators. Global, regional, and national burden of multiple sclerosis 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019 Mar;18(3):269-285. doi: 10.1016/S1474-4422(18)30443-5.
- Mirmosayyeb O, Shaygannejad V, Bagherieh S, Hosseinabadi AM, Ghajarzadeh M. Prevalence of multiple sclerosis (MS) in Iran: a systematic review and meta-analysis. Neurol Sci. 2022 Jan;43(1):233-241. doi: 10.1007/s10072-021-05750-w.
- MS International Federation. Atlas of MS. Available from https://www.atlasofms.org/map/global/epidemiology/number-of-people-with-ms.
- National Guideline on 'e Diagnosis and Management of Multiple Sclerosis in Adults (2019). Ministry of Internally Displaced Persons from the Occupied Territories, Labour, Health and Social Affairs of Georgia. https://www.moh.gov.ge/en/guidelines/.
- O'Connell K, Tubridy N, Hutchinson M, McGuigan C. Incidence of multiple sclerosis in the Republic of Ireland: A prospective population-based study. Mult Scler Relat Disord. 2017 Apr;13:75-80. doi: 10.1016/j.msard.2017.02.010.
- Richard J. Rossi. Applied Biostatistics for the Health Sciences, 2nd Edition. Wiley. 2022. 688.
|
| Publication of the article |
«World of Medicine and Biology» №1(91), 2025 year, 016-020 pages, index UDK 616.-36.22 |
| DOI |
10.26724/2079-8334-2025-1-91-16-20 |
