English Українська
  • Main
  • Useful links
  • Information for Contributors
  • About
  • Editorial board

  • Article
    O. M. Romaniuk, N. M. Rudenko

    REPEATED INTERVENTIONS AFTER TOTAL REPAIR IN PATIENTS WITH TETRALOGY OF FALLOT


    About the author: O. M. Romaniuk, N. M. Rudenko
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation Tetralogy of Fallot occurs in 3.5 % of all congenital heart defects. The total correction consists in eliminating the obstruction of the right ventricular outflow tract using two main techniques: transannular patch and valve-sparing repair – non-transannular patch. The long-term results of 1352 radical corrections of tetralogy of Fallot performed at the Ukrainian Cardiac Center from 1999 to 2022. The the median age of patients at the time of surgery was 9.8 months. The use of transannular patch was 64.2 %, and Non-transannular patch – 35.8 %. The total mortality was – 3.46 %. Reinterventions were performed in 213 (16.5 %) patients. The most procedures were associated with pulmonary artery valve insufficiency (55.5 %) and right ventricular outflow tract obstruction (40.7 %). Analysis of risk factors showed that the use of transannular patch is an independent risk factor for repeated operations (r=0.726, p<0.001).
    Tags congenital heart defects,palliation,surgical correction,endovascular interventions,transannular plasty,valve-sparing surgery
    Bibliography
    • Arafat AA, Elatafy, EE, Elshedoudy S, Zalat M, Abdallah N, Elmahrouk A. Surgical strategies protecting against right ventricular dilatation following tetralogy of Fallot repair. J Cardiothorac Surg. 2018 Jan 22;13(1):14. doi: 10.1186/s13019-018-0702-0.
    • Balasubramanya S, Zurakowski D, Borisuk M, Kaza AK, Emani SM, Del Nido PJ, et al. Right ventricular outflow tract reintervention after primary tetralogy of Fallot repair in neonates and young infants. J Thorac Cardiovasc Surg.2018; 155(2):726–734. doi: 10.1016/j.jtcvs.2017.09.019.
    • Blais S, Marelli A, Vanasse A, Dahdah N, Dancea A, Drolet C, et al. Comparison of long-term outcomes of valve-sparing and transannular patch procedures for correction of tetralogy of Fallot. JAMA Netw open. 2021; 1;4(7):e2118141. doi:  10.1001/jamanetworkopen.2021.18141.
    • Vida VL, Guariento A, Zucchetta F, Padalino M, Castaldi B, Milanesi O, Stellin G. Preservation of the pulmonary valve during early repair of tetralogy of fallot: surgical techniques. Pediatric Cardiac Surgery Annul. 2016;19:75–81 https://doi.org/10.1053/j.pcsu.2015.12.008.
    • Mashali M H, Yousef A A , Elmahrouk A F, Ba-Atiyah W, Rasol M A, Arafa M A, Shihata M S, et al. Reintervention after repair of tetralogy of Fallot: a one-decade single-center experience. Cardiothorac Surg. 2023;31(5). https://doi.org/10.1186/s43057-023-00096-9].
    • Padalino M A , Pradegan N, Azzolina D, Galletti L, Pace Napoleone C, Agati S, et al. The role of primary surgical repair technique on late outcomes of tetralogy of Fallot: a multicentre study. Eur J Cardiothorac Surg. 2020;57:565–573 doi:  10.1093/ejcts/ezz270.
    • Siddiqi U, Adewale A, Pena E, Schulz K, Ilbawi M, El‐Zein Ch, et al. Preserving the pulmonary valve in Tetralogy of Fallot repair: Reconsidering the indication for valve‐sparing. J Card Surg. 2022 Nov 15;37(12):5144–5152. doi: 10.1111/jocs.17156.
    • Ergün S, Genç S B, Yıldız O, Öztürk E, Güneş M, Onan İ S, et al. Predictors of a complicated course after surgical repair of tetralogy of Fallot. Turk Gogus Kalp Damar Cerrahisi Derg. 2020 Apr 22;28(2):264-273. doi: 10.5606/tgkdc.dergisi.2020.18829.
    • Yi K, Wang D, Xu J, Zhang X, Wang W, Gao J, et al. Surgical Strategies for Preservation of Pulmonary Valve Function in a Radical Operation for Tetralogy of Fallot: A Systematic Review and Meta-Analysis. Front Cardiovasc Med. 2022 Jul 13:9:888258. doi: 10.3389/fcvm.2022.888258.
    • Ye XT, Buratto E, Konstantinov IE, d'Udeken Y. Does transatrial‐transpulmonary approach improve outcomes compared with transventricular approach in non‐neonatal patiets undergoing tetralogy of Fallot repair? Interact Cardiovasc Thorac Surg. 2019;29:960–966.
    • Gebauer R, Chaloupecky V, Hucin B, Tláskal T, Komárek A, Janoušek J. Survival and Freedom From Reinterventions in Patients With Repaired Tetralogy of Fallot: Up to 42‐Year Follow‐Up of 917 Patients. J Am Heart Assoc. 2023 Oct 17;12(20):e024771. doi: 10.1161/JAHA.121.024771.
    Publication of the article «World of Medicine and Biology» №1(91), 2025 year, 097-100 pages, index UDK 616-039.75
    DOI 10.26724/2079-8334-2025-1-91-97-100