Avetikov D. S., Yeroshenko H. A., Skrypnyk V. M.

MORPHOLOGICAL AND FUNCTIONAL SUBSTANTIATION OF PREVENTION OF THE POSTOPERATIVE KELOIDAL SCARS OF THE FACE AND NECK

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Об авторе:	Avetikov D. S., Yeroshenko H. A., Skrypnyk V. M.
Рубрика	ЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНА
Тип статьи	Научная статья.
Аннотация	The development and improvement of methods of prevention of keloidal scars is an actual task. The effectiveness of existing methods of prevention of scars remains insufficient. Lipin solution and Dermofibraze cream applied for prevention in the patient with diagnosed polymorphism of the elastin gene g28197 A > G; the histological examination of biopsy were performed during the prevention every 3 month. In 12 months of observation of the skin structure at the site of operation, there was found that the structure of the skin matched the histological organization of mature hypertrophic scar, which confirmed the histological study. Considering above-mentioned, the use of Dermofibraze cream and Lipin liposome preparation would be appropriate for the purpose of prevention of pathological scarring already in the early stages of healing of postoperative wounds.
Ключевые слова	postoperative scar, pathological scar, prevention, microcirculation
Список цитируемой литературы	Неклюдов А.Д. Коллаген: получение, свойства и применение: монография / А.Д. Неклюдов, А.Н. Иванкин. М.: Изд-во Моск. гос. ун-та леса, 2007. - 334 с. Озерская О.С. Рубцы кожи и их дерматокосметологическая коррекция / Озерская О.С. – СПб. : ОАО «ИскусствоРоссии»,2007.–224с. Brudnik U. Therapeutic problems connected with keloid treatment-new treatment possibilities. [Article in Polish]. / U. Brudnik, M. Podolec-Rubis, A. Wojas-Pelc // Przegl Lek.- 2006.-Vol.63, № 9.-P. 803-806. España A. Bleomycin in the treatment of keloids and hypertrophic scars by multiple needle punctures / A. España, T. Solano, E. Quintanilla // Dermatol. Surg.- 2001.- Vol.27, № l.-P. 23-27. Reid R. R. Inhibition of procollagen C-proteinase reduces scar hypertrophy in a rabbit model of cutaneous scarring / R.R. Reid, J.E. Mogford, R. Butt // Wound Repair Regen. -2006.-Vol.14, № 2.-P. 138-141.
Публикация статьи	«Мир Медицины и Биологии» №1(36), 2013 год, 085-087 страницы, код УДК 617.51/.53-003.9-084