MORPHOMETRIC AND MORPHOLOGICAL FEATURES OF RAT BRONCHUS-ASSOCIATED LYMPHOID TISSUE UNDER THE IMPACT OF THE COMPLEX OF FOOD ADDITIVES

Authors:

Abstract:

The paper presents the results of a morphometric and morphological study of the broncho-associated lymphoid tissue of the lungs of rats under the complex action of food additives. It was established that the use of a complex of monosodium glutamate, sodium nitrite and Ponceau 4R leads to a change in morphometric indicators, due to the occurrence of local protective barrier tension phenomena, which was expressed by the formation of secondary lymphoid follicles in the composition of broncho-associated lymphoid tissue, with wave-like changes in cellular representation, which reflected the process antigen-dependent differentiation of immune cells, which was confirmed by an increase in the number of lymphocytes against the background of a decrease in plasma cells and vice versa, and an expansion of the lumen of the vessels of the microcirculatory bed, due to the migration of immunocompetent cells due to the constant and long-term action of a non-specific factor formed by the components of the complex of food additives.

Keywords:

food additives broncho-associated lymphoid tissue microcirculatory bed lymphocytes plasma cells macrophages lungs rats

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Publication:

«World of Medicine and Biology» Vol. 19 No. 85 (2023) , с. 209-215
УДК 311.018.616.23/.24.599.323.4:641

DOI:

https://doi.org/10.26724/2079-8334-2023-3-85-209-215