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Clinical medicine

MINIMALLY INVASIVE VERSUS SURGICAL SOLUTIONS FOR CHRONIC ANAL FISSURE

Published 2026-03-25

Authors:

G.Kh. Abdiyeva
Azerbaijan Medical University image/svg+xml
https://orcid.org/0000-0003-3810-2531
M.F. Amirova
Azerbaijan Medical University image/svg+xml
https://orcid.org/0000-0001-5598-6995
E.V. Nabiyeva
Azerbaijan Medical University image/svg+xml
https://orcid.org/0000-0002-4786-8670
M.M. Mursalov
Azerbaijan Medical University image/svg+xml
https://orcid.org/0000-0002-7210-8681
Abstract:
Chronic anal fissure is a common anorectal disorder associated with considerable morbidity. Lateral internal sphincterotomy is regarded as the gold standard because of its consistently high healing rates, while botulinum toxin injection has been proposed as a less invasive alternative. This study evaluated 48 female patients with chronic anal fissure, divided equally into two groups: botulinum toxin injection (24 patients) and lateral internal sphincterotomy (24 patients). The mean age was similar between groups at approximately 37 years. At twelve months, healing was higher in the lateral internal sphincterotomy group (95.8 %) compared with the botulinum toxin injection group (75 %), though this difference did not reach statistical significance (p=0.0532). Repeat injection was required in 12.5 % of patients. Transient incontinence occurred in 12.5 % of botulinum toxin patients but resolved, whereas 8 % of surgical patients reported persistent incontinence at one year. Botulinum toxin offered faster recovery and fewer complications.
Keywords:
chronic anal fissure botulinum toxin injection lateral internal sphincterotomy recurrence incontinence
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Publication:
«World of Medicine and Biology» Vol. 22 No. 1 (2026) , с. 7-12
УДК 616.35-002-089+615.814
DOI:
https://doi.org/10.26724/2079-8334-2026-1-95-7-12