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    Lugin I.

    SPECIAL CHARACTERISTIC TISSUAL INTERACTIONS IN MORPHOGENESIS IN ORGANS WITH THE HETEROGENEOUS ORIGIN OF TISSUE COMPONENTS


    About the author: Lugin I.
    Heading EXPERIMENTAL MEDICINE
    Type of article Научная статья
    Annotation The studies used the prostatic and seminal vesicles specimens of the humans and rats fetus for examination the regional differentiation of mesenchyme during organogenesis. Fixed, that morphogenesis of vascular endothelium of microcirculatory bed in prostate gland and seminal vesicles during prenatal development have been illustrated by the general laws of morphological transformations in mesenchymic derivatives which is result of interaction between epithelial, stromal and vascular components during formation of functional units in ontogenesis. The maine law is the mechanism of formation of haemocapillaries by as result of aggregation the clusters of cells in mesenchyme with formation of intercellular channels which is lined flattened primary endothelial cells which is supported by apoptosis of some cells with continues regional differentiation. The vasculogenesis in prostate gland and seminal vesicles is unequal and а sinchronic process wich is depended from regional organization of the prostate gland that is evidenced to stromal hypothesis, in which localized areas of stroma perform different functions in regulating epithelia.
    Tags mesenchyme, microcirculatory bed, regional differentiation, provisional principle, morphogenesis
    Bibliography
    • Лили Р. Патогистологическая техника и практическая гистохимия; [пер. с англ. В.В.Португалова] / Р. Лили. – М.: Мир, 1969. –645с.
    • Лугин И.А. Роль мезенхимы в морфогенезе органов с гетерогенной закладкой тканевых компонентов / И.А. Лугин, Б.В. Троценко // Анатомо-хірургічні аспекти дитячої гастроентерології. Матеріали 2-го наукового симпозіуму. – Чернівці, 2010. – С. 84-85.
    • Соловьев Г. С. Роль принципа провизорности в реализации филэмбриогенезов / Г.С. Соловьев, В.Л. Янин, В.Д. Новиков // Морфология. – 2005. – Т.128, №4. – С.14 –18.
    • Троценко Б.В. Региональная гетерогенность мезенхимы в процессах морфогенеза предстательной железы у плодов человека и крысы / Б.В.Троценко, И.А.Лугин // Морфологія – 2009 – Т.III, № 3, – С. 101 – 105.
    • Чорнокульський С.Т. Ембріон-та мікроваскулогенез передміхурової залози людини / С.Т. Чорнокульський, І.С. Чорнокульський // Клінічна анатомія та оперативна хірургія. – 2006 – Т. 5, №2. – С. 85.
    • Johansson  A. Altered Levels of Angiopoietin 1 and Tie 2 Are Associated with Androgen-Regulated Vascular Regression and Growth in the Ventral Prostate in Mice and Rats / А. Johansson, S. Haggstrom, А. Bergh // Endoc. – 2005. – Vol. 146, №8. – Р. 3463 – 3470.
    • Tuxhorn J.A. Reactive Stroma in Human Prostate Cancer: Induction of Myofibroblast Phenotype and Extracellular Matrix Remodeling / J. А. Tuxhorn, G. Е. Ayala, М. J. Smith // Clin. Cancer Res. – 2002. – Vol. 8. – Р. 2912 – 2923.
    • Vilamajor P.S.L. Postnatal Growth of the Ventral Prostate in Wistar Rats: A Stereological and Morphometrical Study / P.S.L. Vilamajor, S.O.R. Taboga, Н. F. Carvalho // Anat. Rec. Part A. – 2006. – Vol. 288A – Р. 885 – 892.
    Publication of the article «World of Medicine and Biology» №4(35), 2012 year, 077-079 pages, index UDK 611. – 018: 612. 112. 93: 611 .637