Article
FREQUENCY AND CRITERIA OF DEGREE OF EXPRESSIVENESS NOT DIFFERENTIATED DYSPLASIA A CONNECTIVE TISSUE AT LEІOMYOMA A UTERUS AT WOMEN OF REPRODUCTIVE AGE
About the author: | Zaporozhchenko M. B. |
Heading | CLINICAL MEDICINE |
Type of article | Scentific article |
Annotation | The work purpose was studying of frequency and criteria of degree of expressiveness not differentiated dysplasia a connective tissue at leіomyoma a uterus at women of reproductive age. 300 women of reproductive age on presence of clinical signs not differentiated dysplasia a connective tissue are surveyed. Defined the maintenance of the general hydroxy-proline and glycosoaminoglicans. On the average signs not differentiated dysplasia a connective tissue are found in 26,3 % of women with leіomyoma a uterus. At presence leіomyoma proliferativ type concentration of the general hydroxy-proline reached 101,9±6,1 mg/d that was essential more (р <0,001) in 3,7 times in relation to control bunch and in 1,5 times in comparison with bunch of women for which it is diagnosed simple leіomyoma. The maintenance glycosoaminoglicans in urine of women with leіomyoma proliferativ type was above in 3,2 times in relation to bunch of control and in 2,1 times in relation to bunch of women about simple leіomyoma that testifies to degree of infringement of exchange processes in a connective tissue. One of new concepts aetiology factors of occurrence and pathogenetic mechanisms of progressing of growth leіomyoma a uterus is infringement of a metabolism of a connective tissue in the form of not differentiated dysplasia a connective tissue in which basis the pathology сollagen formation lies. |
Tags | not differentiated dysplasia a connective tissue, hydroxy-proline, glycosoaminoglicans, leіomyoma a uterus |
Bibliography |
|
Publication of the article | «World of Medicine and Biology» №3(45), 2014 year, 047-050 pages, index UDK 618.14-006.363.03-06:616-018.2-002.44 |