English Українська
  • Main
  • Useful links
  • Information for Contributors
  • About
  • Editorial board

  • Article
    Kuzmenko Y. Y.

    FATTY-ACID COMPOSITION OF KIDNEY TISSUE IN EXPERIMENTAL ANIMALS WITH CONGENITAL HYPOTHYRIOSIS


    About the author: Kuzmenko Y. Y.
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation This paper presents the results of studies of fatty acids in the tissues of the kidneys in the dynamics of development of congenital hypothyroidism. Congenital hypothyroidism in animals modeled by inhibiting thyroid using tireostatika - merkazolila. Predominant acids renal tissue of the control group were palmitic, stearic and oleic fatty acids that typically prevail in all other tissues of humans and animals. After 14 days from the start of the experiment is reduced, compared with age-controlled percentage of saturated fatty acids. After 50 and 100 days of congenital hypothyriosis redistribution of saturated and unsaturated fatty acids acquires character opposite to that observed after 14 days of the experiment: fatty acids content increases and EFAs - decreases as compared with age-control.
    Tags kidney, congenital hypothyriosis, fatty acids
    Bibliography
    • Berezov T. T. Biologicheskaya himiya / T. T. Berezov, B. V. Korovin // - M.: Meditsina, - 2004. - S. 387-392.
    • Zaharova I. N. Rol polinenasyischennyih zhirnyih kislot v formirovanii zdorovya detey / I. N. Zaharova, E. N. Surkova // Pediatriya. - 2009. - T. 8, No 6. - S. 84-91.
    • Patent No27821, Ukrayina, MPK G09B23/28(2006.01) Sposib modelyuvannya gIpotireozu u schurIv // Stechenko L.O., Petrenko V.A., Bik P.L., Kuzyan V.R., Kuftireva T.P.; Natsionalniy medychniy universytet im. O.O. Bogomoltsya-No u200708689; Zayavl. 30.07.2007. 
    • Titov V. N. Narushenie transporta v kletki nasyischennyih zhirnyih kislot v patogeneze essentsialnoy gipertonii (obzor literatury) / V. N. Titov // Klin. lab. diagnostika. - 1999. - No 2. - S. 3-9.
    • Dutta-Roy A. K. Transport mechanisms for long-chain polyunsaturated fatty acid in the human placenta / A. K. Dutta-Roy // Am. J. Clin. Nutr. - 2000. - Vol. 71, № 1. - P. 315-322.
    • Haggarty P. Effect of placental function on fatty acid requirements during / P. Haggarty // Am. J. Clin. Nutr. 2004. Vol. 58. P.1559-1570.
    • Springer M. Fatty acid-binding protein: fuel metabolism / M. Springer, L. Dordrecht // Molec. and cell. bioch. - 2007. - Vol. 299, № 1-2. - P. 75-84.
    Publication of the article «World of Medicine and Biology» №4(47) 2 part 2014 year, 144-147 pages, index UDK 616.441-008.64-053.1:612.08