Fushtey I. M., Tokarenko O. O.

LEFT VENTRICULAR STRUCTURAL AND FUNCTIONAL ALTERATIONS IN PATIENTS WITH STAGE II ESSENTIAL HYPERTENSION

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About the author:	Fushtey I. M., Tokarenko O. O.
Heading	CLINICAL MEDICINE
Type of article	Scentific article
Annotation	Arterial hypertension (AH) causes both remodeling of left ventricular (LV) and worsening of renal function, therefore studying the relationship between cardiac and renal pathology in this aspect is very important. The aim was to identify the characteristics of intracardiac hemodynamics and remodeling of LV in patients with essential hypertension (EH) II stage complicated by nephropathy. There were examined two groups of patients with EH stage II of the second (n=31) and third (n=31) degree of AH with nephropathy, as well as three comparison groups, including patients with EH stage II of the second (n=31) and third (n=31) degree of AH without nephropathy and practically healthy persons (n=31). The ratio value of albumin/creatinine content in urine ≥ 30 mg/d was regarded as a marker of kidney disorder. Echocardiographic study was conducted by conventional methods. It was revealed that in patients with EH stage II of the second and third degree hypertension and nephropathy there are significant changes of the morphometric and volumetric parameters of the LV. In patients with EH stage II and nephropathy significantly greater changes of left ventricular transmitral blood flow are manifested comparing with patients with EH stage II without nephropathy. There was detected a significant increase of pathological LV geometry types with prevalence of concentric remodeling and concentric hypertrophy in patients with EH stage II and nephropathy in comparison with patients with EH stage II without nephropathy.
Tags	hypertensive nephropathy, left ventricular geometry types, cardiac remodeling, diastolic dysfunction
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Publication of the article	«World of Medicine and Biology» №3(52) 2 part 2015 year, 048-053 pages, index UDK 616.61:616.12-008.331.1:616.127-073.432.19