O. G. Popadynets

MEDICAL AND SOCIAL PROBLEM OF HEMATOLOGIC DISEASES OF UKRAINIAN POPULATION

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About the author:	O. G. Popadynets
Heading	LITERATURE REVIEWS
Type of article	Review article
Annotation	The central organ of hemopoiesis and immune protection is a red bone marrow that contains not only hemopoietic stem cells, but also it forms a unique microenvironment for their proliferation and differentiation. It is a red bone marrow that regulates access to peripheral blood of mature blood corpuscle. Pathological deviations in the blood system are considered to be an increase or decrease in the quantitative composition of individual cells, as well as changes in their ratios relative to each other, or changes in their form.
Tags	red bone marrow, diseases of the blood system, stem cells
Bibliography	Ado A. D. Pathological Physiology: a textbook for Medical Universities / A.D. Ado [and others]. // - M .: Triada-X, - 2000. - 574 p. Afanasyev Yu. I. Histology, embryology, cytology: a textbook / Yu.I. Afanasyev, N. A. Yurina, E. F. Kotovsky [and others] // - M.: Medicine, - 201 - 800 p. Astrelina T. A. Evaluation of the quality and safety of cryopreserved multipotential mesenchymal placental stromal cells in clinical practice / T.A. Astrelina, A. E. Gomziakov, I.V. Kobzeva // Genes and cells. - 2013. - Vol. 8, № 4. - P. 82-87. Banadiha N.V. Clinical aspects of iron deficiency anemia in children of early age / N.V. Banadiha, Ya.V. Rogalska // Perinatology and pediatrics. - 2013. - № 2. - P. 82-85. Banadiha N.V. Influence of iron deficiency anemia in children on the formation of systemic immunity / N.V. Banadiha, Ya.V. Rogalska, I.O. Rogalsky // Modern Pediatrics. - 2014. - №. 3. - P. 40-43. Bokova T. A. Iron deficiency states in adolescents: Principles of correction / T. A. Bokova, G. V. Maslikova // Doctor in charge. - 2014. - №9. - P. 49-51. Belyh N.A. Prediction of the risk of anemia formation in infants / N. A. Belyh // Modern Pediatrics. - 2015. - № 1. - P. 34-39. Vydyborets S.V. Iron deficiency anemia: [educational and methodological guide for students and postgraduate students of higher medical educational institutions of III-IV accreditation levels] / S.V. Vydyborets, S.M. Gaidukova, O.I. Chornobrova [and others] // - Vinnitsa; Borispol: Mercury-Podillya, 2012. - 237 p. Vinogradova M.A. Anemia in pregnancy: algorithms for diagnosis and treatment of iron deficiency / M.A.Vinogradova, T. A. Fedorova, O. V. Rogachevsky // Obstetrics and gynecology. – 2014. – № 8. – P. 137-142. Herman S.I. Justification of the use of placental drugs in the complex treatment of generalized periodontitis: dissertation ... PhD in Medicine: 14.01.22 / S. I. Herman; Kharkiv state medical university  – Kharkiv, - 2003.  – 157 p. Grishchenko V.V. Phagocytic activity of segmented neutrophil of rats with induced generalized periodontitis and its correction using cryopreserved extracts of human placenta / V.V. Grishchenko // Problems of ecological and medical genetics and clinical immunology: collection of the research works. – K., 2004.  – Ed. 5 (58).  – P. 59-68. Grishchenko V.I. Achievements of cryobiology and cryomedicine in the name of the health of the nation / V.I. Grishchenko // Issues of Cryobiology. – 2008. –Vol. 18, № 3.  – P. 269-274. Grishchenko V.I. Placenta: cryopreservation, structure, features, perspectives of clinical application / V. I. Grishchenko, T. N. Yurchenko, A.N. Goltsev [and others] // - Kharkiv: Brovin A.V., - 2011.  – 268 p. Danilov R. K. Histology. Embryology. Cytology / R.K. Danilov. – M.: MIA, 2006. -454 p. Erman M.V. Iron deficiency anemia in children / M.V. Erman // Modern Pediatrics .- 2014.- № 4. P. 22-25. Zaporozhan V.N. Stem Cells / V.N. Zaporozhan, Yu. I. Bazhora // - Odessa: Odessa  medical university, - 2004.  – 227 p. Zayko N. N. Pathological Physiology: Textbook / N. N. Zayko, Yu.V. Byts’, A. V. Ataman [and others] //  – М.: MEDpress-inform, - 2008.  –  635 c . Zakharova I. N. Deficiency of iron in children of early age and methods of its correction / I. N. Zakharova, A. N. Goryainova, Ye. B. Machneva [and others] // Issues of modern pediatrics. – 2013.  – T. 12, № 2.  – P. 52-58. Zakharova I. N. Anemia syndrome in pediatric practice: differential diagnosis and therapy / I. N. Zakharova, Yu. A. Dmitrieva // Modern Pediatrics.  – 2015. –  № 1.  – P. 23-28. Kutsevlyak V.F. Experimental study of the state of the prooxidant-antioxidant balance of animals in the dynamics of induced generalized periodontitis and its correction with cryopreserved extracts of human placenta / V.F. Kutsevlyak, V.V. Grishchenko, Yu. V. Nikitchenko // Issues of cryobiology. – 2008. –  Vol. 18, № 4.  – P. 482-485. Kazyukova T. V. The strategy of treatment of iron deficiency anemia in children of early age / T. V.Kazyukova [and others] // Pediatrics. G.N.Speransky Journal. – 2012. – Vol. 91, № 4. – P. 89-97. Lipunova Ye.A. The system of red blood: Comparative physiology: a monograph / Ye. A. Lipunova, M. Yu. Skorkina.  – Belgorod: Publishing house BelGu, 2004.  – 216 p. Lutsyk O. D. Human Histology: a textbook for students of higher educational institutions of III-IV accreditation levels] / O. D. Lutsyk, A. Y. Ivanova, K. S. Kabak, Yu. B. Tchaikovsky.  –4th ed.- K.: Knyha Plus, - 2013. – 582 p. Maltseva T.V. Features of therapy of iron deficiency anemia in children of the first year of life in different types of feeding / T.V. Maltseva, S.P. Repina // Issues of practical pediatrics.  – 2012, T. 7, № 4. – P. 57-59. Nikolayeva L.P. Features of the myelogram of bone marrow in tubular bones / L.P. Nikolaeva, D.V. Cherdantsev, N.S. Hvat // Modern issues of science and education. – 2015. – №4. Pogranichna H. R. Replacement of postoperative bone cavities of jaws by osteoplastic material from placental tissue: abstract of a thesis for obtaining PhD in medicine / H. R. Pogranichna; Lviv National D. Halytsky Medical University.  – Lviv, - 2006. - 18 p. Prokopyuk O. S. Cryopreservation of placenta of different degrees of maturity / O. S. Prokopyuk, A. Yu. Petrenko, V. Yu. Prokopyuk [and others] // Issues of cryobiology. – 2008. - Vol. 18, № 2.  – 220 p. Prokopyuk O. S. Morphofunctional preservation of placenta fragments under different cryopreservation schemes / O. S. Prokopyuk, V. Yu. Prokopyuk // Problems of cryobiology.  – 2012. – Vol. 22, № 3.  – 264 p. Serikov V.B. Human placenta as a source of hematopoietic stem cells / V.B. Serikov, F. Kuipers // Cellular transplantology and tissue engineering. – 2008. – T. III, №. 2.–  P. 51-56. Tretyak N.M. Hematology. Textbook / N. M. Tretyak // - K. Foreign trade -2005, 240 p. Tretyakova O. S. Algorithm for diagnostics of iron deficient states in pediatric practice / O. S. Tretyakova // Children's doctor. - 2014. - № 5. - P. 38-44. Cherkasov V.G. Anatomy of a man / V.G. Cherkasov, S.Yu.Kravchuk; NMU, Bukovyn. DMU - Vinnitsa: Nova Knyha, - 2011. - 639 p. Shabliy V. A. Gaining of mesenchymal stem cells from cryopreserved placental tissue / VA Shabliy, G.S. Lobyntseva, M.D. Kuchma [and others] // Cellular transplantology and tissue engineering. - 2010. - Vol. 5, № 3. - P. 52-53. Shabliy V.A. Characteristic of multipotent mesenchymal stromal cells obtained from human placenta / V. Shabliy, M. Kuchma, V. Kirik [and others] // Cellular transplantation and tissue engineering. - 2012. - T. VII, № 4. - P. 55-61. Shabliy V. A. Cryopreservation of human placenta tissue - a source of hematopoietic progenitor cells and multipotent mesenchymal stromal cells / V. A. Shabliy, M. D. Kuchma, V. M. Kirik [and others] // Cellular transplantation and tissue engineering  – 2012. – Vol. 7, № 1. - P. 54-62. Shabliy V. Mesenchymal stromal cells from the native and cryopreserved human placenta: phenotype, multipotency and migration potential in vivo / V. Shabliy, M. Kuchma, V. Kirik [and others] // Issues of cryobiology. - 2012. - T. 22, № 2. - P. 157-160. Shchulipenko I.M. Clinical picture and diagnostics of syndromes and diseases of the hemapoietic system: a textbook for senior students of medical universities, masters, internists and cadets on specialty. "General Practice - Family Medicine" / I. M. Shchyulpenko, Yu. M. Goldenberg, T.V. Nastroh [and others] //. - Poltava: Techservice, 2011. - 325 p. Yartseva V. Yu. A New View on the Prevention of Iron Deficiency Conditions in Children older than one year old / V.Yu. Yartseva // Doctor in charge. – 2012. – № 8. – P. 37-41. Baker R. D. Diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants and young children (0-3 years of age) / R. D. Baker, F. R. Greer // - Pediatrics. – 2010. – № 126 (5). – P. 1040–1050. Bárcena A. Human placenta and chorion: potential additional sources of hematopoietic stem cells for transplantation / A. Bárcena, M. O. Muench, M. Kapidzic [et al.] // Transfusion. – 2011. –Vol. 51. – 94–105. Jordan R. G. Prenatal and postnatal care : a woman-centered approach / R. G. Jordan, J. Marfell,J. Engstrom [et al.] // – Ames, Iowa: Wiley-Blackwell, - 2014. – 668 p. Parolini O. Concise review: isolation and characterization of cells from human term placenta: outcome of the first international Workshop on Placenta Derived Stem Cells / O. Parolini, F. Alviano, G. P. Bagnara [et al.] // Stem Cells. – 2008. – Vol. 26. – P. 300–311. Rodak B. Hematology: Clinical Procedure and Applications. – 2 nd ed. / B. Rodak [et al.] // – Philadelphia: WB Saunders, - 2002. – 835 p.
Publication of the article	«World of Medicine and Biology» №3(61), 2017 year, 181-184 pages, index UDK 616.15:614.2(477)
DOI	10.26724/2079-8334-2017-3-61-181-184