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    A. M. Goltsev, O. O. Lykhytskyi

    PROGNOSIS OF REPARATIVE OSTEOGENESIS IN RATS WITH OPEN MANDIBULAR FRACTURE ON THE BACKGROUND OF OSTEOPOROSIS


    About the author: A. M. Goltsev, O. O. Lykhytskyi
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation In this work, mathematical prediction of the course of reparative osteogenesis in rats with an open fracture of the mandible on the background of osteoporosis has been carried out. It is shown that important biochemical markers for prognosis of osteo-reparation processes under conditions of simulated pathology are the content of VEGF, TGF-β1, carbonyl groups of proteins, nitrites and nitrates in serum. Among these biochemical indicators, the greatest value for controlling the processes of reparative osteoregeneration is the determination of the content of TGF-β1 and VEGF in serum, but less important is the study of the level of carbonyl groups of proteins and nitrites and nitrates in serum.
    Tags metabolic markers, reparative osteogenesis, fracture of the mandible, mathematical prediction
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    Publication of the article «World of Medicine and Biology» №1(63), 2018 year, 109-112 pages, index UDK (611.018.4+599.323.4):616.716.4
    DOI 10.26.724/2079-8334-2018-1-63-109-112