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    S.O. Zubchenko, O. Sharikadze

    ANALYSIS OF SENSITIZATION FEATURES TO WEED POLLEN AND EFFICACY OF ALLERGEN IMMUNOTHERAPY IN PATIENTS OF THE CENTRAL AND WESTERN REGIONS IN UKRAINE


    About the author: S.O. Zubchenko, O. Sharikadze
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation Incidence of sensitization is changing geographically based on multiple environmental factors. About 1.5 thousand different types of weeds are common in Ukraine. Climatic and geographical conditions such as air temperature, humidity and plant diversity in the region is of great importance in the prevalence of allergic diseases. Allergy to weeds is a global problem due to development of respiratory allergy – seasonal allergic rhino-conjunctivitis (hay fever) with/without bronchial asthma in patients living in Ukraine. Allergen immunotherapy is a disease-modifying treatment for patients with seasonal hay fever with/without bronchial asthma. However, in Ukraine there are little data on the efficacy of sublingual form of allergen immunotherapy. The use of standardized sublingual immunotherapy is efficient in treating patients with seasonal hay fever with/without bronchial asthma.
    Tags Ambrosia, Artemisia, molecular allergodiagnosis, VAS, SLIT efficacy
    Bibliography
    • Asero R, Bellotto E, Ghiani A, Aina R, Villalta D, Citterio S. Concomitant sensitization to ragweed and mugwort pollen: who is who in clinical allergy?. Annals of Allergy, Asthma & Immunology. 2014;113(3):307-13.
    • Bousquet J, Heinzerling L, Bachert C, Papadopoulos NG, Bousquet PJ, Burney PG, et al. Position paper EAACI practical guide to skin prick tests in allergy to aeroallergens. Allergy. 2012;67:18-24.
    • Douladiris N, Savvatianos S, Roumpedaki I, Skevaki C, Mitsias D, Papadopoulos N. A molecular diagnostic algorithm to guide pollen immunotherapy in southern Europe: towards component-resolved management of allergic diseases. International Archives of Allergy and Immunology. 2013;162(2):163-72.
    • Gadermaier G, Hauser M, Ferreira F. Allergens of weed pollen: an overview on recombinant and natural molecules. Methods. 2014;66(1):55-66.
    • Gharib V, Zubchenko S, Chopyak V, Gajewska V, Gajewsky V. The molecular overview of sensitization to weed pollen allergens and its possible clinical application in Ukraine for the optimal allergoimmunotherapy. Zhurnal vushnykh, nosovykh i horlovykh khvorib. 2016;6:28-41.
    • Léonard R, Wopfner N, Pabst M, Stadlmann J, Petersen B, Duus J, et al. A new allergen from Ragweed (Ambrosia artemisiifolia) with homology to Art v 1 from Mugwort. Journal of Biological Chemistry. 2010;285(35):27192-200.
    • Linkov G, Toskala E. Sublingual immunotherapy. Current Opinion in Otolaryngology & Head and Neck Surgery. 2014;22(3):208-10.
    • Matricardi P. Molecular profile clustering of IgE responses and potential implications for specific immunotherapy. Current Opinion in Allergy and Clinical Immunology. 2014;13(4):438-45.
    • Movérare R, Larsson H, Carlsson R, Holmquist I. Mugwort-sensitized individuals from North Europe, South Europe and North America show different IgE reactivity patterns. International Archives of Allergy and Immunology, 2011;154(2):164-172.
    • Niederberger V. Allergen-specific immunotherapy. Immunology Letters. 2009;122(2):131-3.
    • Panzner P, Vachová M, Vítovcová P, Brodská P, Vlas T. A comprehensive analysis of Middle-European molecular sensitization profiles to pollen allergens. International Archives of Allergy and Immunology. 2014;164(1):74-82.
    • Sánchez-López J, Tordesillas L, Pascal M, Muñoz-Cano R, Garrido M, Rueda M, et al. Role of Art v 3 in Pollinosis of Patients Allergic to Pru p 3. Journal of Allergy and Clinical Immunology. 2014;133(4):1018-25.
    • ShupykNationalMedicalAcademy of Postgraduate Education, UkrainianCenter for Scientific Medical Information and Patent License Activities. Algorithm for selecting patients for allergen specific immunotherapy (ASIT). Kiyv; 2011. 311 p.
    Publication of the article «World of Medicine and Biology» №4(66), 2018 year, 056-062 pages, index UDK 616-022.854-092.19-085.218.373(477.4)(477.8)
    DOI 10.26724/2079-8334-2018-4-66-56-62