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    O.Yu. Usenko, A.V. Sydiuk, A.S. Klimas, O.Ye. Sydiuk

    POSTOPERATIVE ANASTOMOTIC COMPLICATIONS IN PATIENTS WITH MALIGNANT TUMORS OF THE ESOPHAGUS AND ESOPHAGEAL GASTRIC JUNCTION CANCER


    About the author: O.Yu. Usenko, A.V. Sydiuk, A.S. Klimas, O.Ye. Sydiuk
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation Formation of esophagogastric anastomosis after esophagectomy, despite apparent progress, is still accompanied by the development of complications associated with anastomosis. However, information about the impact of the method of forming esophagogastric anastomosis on the effects after the esophagectomy remains controversial. The aim of the study – to provide a comparative characteristic of postoperative complications in patients after esophagectomy, depending on the method of forming the mechanical esophagogastric anastomosis. The study included 30 patients who were formed by developed and protected by the Ukrainian patents invagination mechanical esophagogastroanastomosis (study group) and 30 patients who had formed circular mechanical esophagogastroanastomosis end-to-side (comparison group) after esophagectomy. Evaluated the rate of anastomotic leakage, the frequency of benign strictures, the frequency and severity of reflux esophagitis. In the dynamics all patients performed esophagogastroduodenoscopy, the severity of the reflux esophagitis was evaluated according to the modified Los Angeles classification. Statistical analysis of data was carried out using the statistical analysis package EZR v. 1.35 (Saitama Medical Center, Jichi Medical University, Saitama, Japan), Graphic interface to R (The R Foundation for Statistical Computing, Vienna, Austria). In the conditions of the formation of invagination mechanical esophagogastroanastomosis, the results revealed a statistically significant reduction in benign strictures (p=0,047) (17% (95% CІ 5,4% – 32,6%), vs 43% (95% CІ 25,7% – 61,9%), RF=0,4 (95% CІ 0,2 – 0,9), as well as the frequency of postreaction reflux esophagitis (43% vs 68%; p=0,02) in comparison with the circular mechanical esophagogastroanastomosis end-to-side. However, there were no significant differences between the two groups regarding the anastomotic leakage (0% vs 7%, p=0,49). It should be noted that in the conditions of the formation of invagination mechanical esophagogastroanastomosis cases of its leakage were not revealed. The method of formation of the invagination mechanical esophagogastroanastomosis contributes to the reduction of the frequency of benign strictures of anastomosis and reflux esophagitis, anastomotic leakage was not observed.
    Tags mechanical anastomosis, invagination, circulatory, anastomotic leakage, benign stricture, reflux esophagitis
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    Publication of the article «World of Medicine and Biology» №2(68), 2019 year, 135-140 pages, index UDK 616.329-089
    DOI 10.26724/2079-8334-2019-2-68-135-140