| About the author: |
M. M. Kochuieva, V. G. Psarova, H. A. Tymchenko, O. S. Komissarova, A. V. Marchenko, M. Ye. Tymchenko, Yu. O. Zaikina |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The relevance of the study is due to the increased prevalence of the phenotype of bronchial asthma with obesity and its more severe course. The purpose of the study was to investigate the effect of excess body weight on the parameters of the clinical and laboratory condition of patients with bronchial asthma. 132 patients with bronchial asthma (76 women and 56 men), aged 35–60 years, 30 patients with normal weight and 102 patients with a body mass index of 25.0 kg/m2 and more were examined. It was found that overweight patients with bronchial asthma have a longer duration of the disease (by 28.6 %) and corticosteroids (by 27.0 %), higher cardiovascular risk associated with increased diastolic blood pressure (by 5.3 %), decreased high-density lipoprotein (by 65.7 %), an increase in low-density lipoprotein (by 13.2 %) and glucose levels (by 5.1 %), an increase in interleukin-6 (by 31.8 %). Overweight correlations with age, spirometry, and symptom control were found in patients with asthma. |
| Tags |
bronchial asthma, obesity, symptom control, disease course, cardiovascular risk |
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| Publication of the article |
«World of Medicine and Biology» №3(77), 2021 year, 082-086 pages, index UDK 616.248-036.001.33 |
| DOI |
10.26724/2079-8334-2021-3-77-82-86 |
