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    А. І. Yachmin, G. A. Yeroshenko, K. V. Shevchenko, S. V. Hapon, A. V. Vatsenko, N. A. Ulanovska-Tsyba, V. M. Sokolenko

    ULTRASTRUCTURAL CHARACTERISTICS OF THE RAT GASTRIC FUNDIC WALL AFTER THE IMPACT OF THE COMPLEX OF FOOD ADDITIVES


    About the author: А. І. Yachmin, G. A. Yeroshenko, K. V. Shevchenko, S. V. Hapon, A. V. Vatsenko, N. A. Ulanovska-Tsyba, V. M. Sokolenko
    Heading EXPERIMENTAL MEDICINE
    Type of article Scentific article
    Annotation The main submicroscopic changes in the gastric wall of rats after exposure to monosodium glutamate, sodium nitrite and Ponceau 4R were determined. It was found that the effect of a complex of food additives on the mucous membrane of the fundus of the stomach of rats led to a violation of secretion and secretion, which at the ultrastructural level was manifested by violations of architecture and electron density of secretory granules in major exocrinocytes, cervical mucocytes and superficial epithelium. The impact of the complex of food additives on the mucous membrane of the rat gastric fundus is manifested primarily by dystrophic changes in superficial scrobiculus exocrinocytes, which are in direct contact with exogenous factors, as well as in the exocrinocytes of gastric glands; disorders of microcirculation are also noted.
    Tags fundus of stomach, submicroscopic changes, food additives, mucous membrane, rats
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    Publication of the article «World of Medicine and Biology» №2(80), 2022 year, 252-255 pages, index UDK 616.33:613.2:599.323.4:612.08
    DOI 10.26724/2079-8334-2022-2-80-252-255