| About the author: |
G. A. Yeroshenko, I. M. Donets, K. V. Shevchenko, O. B. Riabushko, I. M. Zviaholska, V. V. Onipko, R. V. Peredera |
| Heading |
EXPERIMENTAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
The paper presents the findings of morphometric and morphological studies of the diffuse lymphoid tissue of rat lungs under the combined effect of the food additives. It has been found that the condition of the diffuse lymphoid tissue of rat lungs, under the impact of the complex of food additives comprise of monosodium glutamate, sodium nitrite and Ponceau 4R, reflects the reaction of elements of the local defense barrier to the action of the components of the food additives’ complex, primarily functioning as antigens. This is manifested by the activation of processes of antigen-dependent differentiation of cells of the lymphoid lineage, undulating changes in the morphometric parameters and the degree of vascularization of the diffuse lung tissue. |
| Tags |
food additives,diffuse lymphoid tissue,capillaries,lymphocytes,plasma cells,macrophages,lungs,rats |
| Bibliography |
- Vatsyk MO. Osoblyvosti strukturno-prostorovoi orhanizatsii krovonosnoho rusla lehen shchuriv u normi ta yoho reorhanizatsiia pry zahalnomu znevodnenni. Zdobutky klinichnoi i eksperymentalnoi medytsyny. 2018; 3: 28-35. [in Ukrainian].
- Lykhatskyi PH, Fira LS, Honskyi YaI. Dynamika zmin markeriv bioenerhetychnykh protsesiv ta tsytolizu u shchuriv pislia urazhennia nitrytom natriiu na tli tiutiunovoi intoksykatsii. Visnyk problem biolohii i medytsyny. 2017; 2:147-52. [in Ukrainian].
- Lisnianska NV, Novak–Mazepa KhO, Kopanytsia OM, Mialiuk OP, Pak AI. Vyvchennia efektiv poiednanoi dii kharchovykh dobavok. Visnyk medychnykh i biolohichnykh doslidzhen. 2020; 2: 88-90. [in Ukrainian].
- Shpihelhalter D. Mystetstvo statystyky: Pryiniattia arhumentovanykh rishen na pidstavi danykh. TOV «Vydavnycha hrupa KM-BUKS»; 2023; 384 s. [in Ukrainian].
- Asif Ahmed M, Al-Khalifa AS, Al-Nouri DM, El-din MFS. Dietary intake of artificial food color additives containing food products by school-going children. Saudi J Biol Sci. 2021;28(1):27-34. DOI: 10.1016/j.sjbs.2020.08.025а
- Kay R. Medical statistics. S. Karger Publishers Limited 2020; 108 p.
- Lis K, Bartuzi Z. Natural food color additives and allergies. Alergia Astma Immunol. 2020;25(2):95-103.
- Matsyura O, Besh L, Besh O, Troyanovska O, Slyuzar Z. Hypersensitivity reactions to food additives in pediatric practice: two clinical cases. Georgian Med News. 2020;307:91-5.
- Pronina OM, Koptev MM, SM Bilash SM, Yeroshenko GA. Response of hemomicrocirculatory bed of internal organs on various external factors exposure based on the morphological research data. World of Medicine and Biology. 2018; 1(63): 153-57.
- Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Arjan te Pas et al. European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2019 Update. Neonatology. 2019; 111(4): 432-50.
- Valluzzi RL, Fierro V, Arasi S, Mennini M, Pecora V, Fiocchi A. Allergy to food additives. Curr Opin Allergy Clin Immunol. 2019;19(3):256-262. DOI: 10.1097/ACI.0000000000000528
- Valluzzi RL, Fierro V, Arasi S, Mennini M, Pecora V, Fiocchi A. Allergy to food additives. Curr Opin Allergy Clin Immunol. 2019;19(3):256-262. DOI: 10.1097/ACI.0000000000000528
- Yachmin AI, Kononov BS, Yeroshenko GA, Bilash SM, Bilash VP. Ameasure of the effect of complex food additives on rats’adaptive responses. World of Medicine and Biology. 2020; 1(71): 232-35.
- Yeroshenko GА, Donets IM, Shevchenko KV, Vatsenko AV, Ulanovska-Tsyba NA, Rіabushko OB, Klepets OV. Morphometric and morphological features of rat bronchus-associated lymphoid tissue under the impact of the complex of food additives. World of Medicine and Biology. 2023; 3(85): 209-216.
- Zanfirescu A, Ungurianu A, Tsatsakis AM, Nițulescu GM, Kouretas D, Veskoukis A, Tsoukalas D, Engin AB, Aschner M, Margină D. A review of the alleged health hazards of monosodium glutamate. Compr Rev Food Sci Food Saf. 2019;18(4):1111-34. doi: 10.1111/1541-4337.12448.
|
| Publication of the article |
«World of Medicine and Biology» №4(86), 2023 year, 193-197 pages, index UDK 616.24:613.29:[612.08:599.323.4] |
| DOI |
10.26724/2079-8334-2023-4-86-193-197 |
