| About the author: |
R. P. Tkachenko, N. Yu. Kondratyuk, O. G. Kuryk, O. M. Mostiuk, L. A. Cherkasova, K. V. Bazdyrev, O. L. Kisilenko |
| Heading |
CLINICAL MEDICINE |
| Type of article |
Scentific article |
| Annotation |
Secondary hyperparathyroidism develops in patients with chronic kidney disease due to stimulation of the thyroid gland with the emergence of autonomy of their function, which causes metastatic calcification and calciphylaxis. If conservative treatment of this pathology is ineffective, subtotal parathyroidectomy is performed. The purpose of the study was to compare the results of surgical and conservative treatment of patients with secondary hyperparathyroidism with calcification and calciphylaxis. Patients with medical treatment had complaints of pain in the bones and joints, itchy skin, convulsions, while in patients after surgery the symptoms had a clear tendency to decrease. There was the healing of trophic ulcers of the skin, a decrease in the size of calcifications in 2–3 months and their disappearance in a year after parathyroidectomy. Parathyroid hormone levels dropped to normal within a few days after surgery, and calcium and phosphorus levels dropped to safe levels. Therefore, surgery is an effective treatment for patients with chronic kidney disease, as it quickly normalizes laboratory parameters, eliminates clinical manifestations, reduces the manifestations of metastatic soft tissue calcification and intravascular deposition of calcium salts. |
| Tags |
secondary hyperparathyroidism, metastatic calcification, calciphylaxis, chronic kidney disease, subtotal parathyroidectomy |
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| Publication of the article |
«World of Medicine and Biology» №1(79), 2022 year, 147-151 pages, index UDK 616 - 008.9 – 06:616.381 – 005.4 – 091.8 |
| DOI |
10.26724/2079-8334-2022-1-79-147-151 |
